Evidence map›Paper›PMID 40791158›Full record

ArticleActa oncologica (Stockholm, Sweden)2025

Telemedicine follow-up for pre-malignant and malignant glottic lesions: a randomised controlled trial study protocol comparing care close to home versus standard of care.

Nathalie F Van Rhee, Rosanne C Schoonbeek, Inge Wegner, Karin M Vermeulen, Robert C Maat, Dirk A Dietz de Loos, György B Halmos, Boudewijn E C Plaat

Abstract readClinical Trial Protocol
In one paragraph

Article in Acta oncologica (Stockholm, Sweden), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nathalie F Van RheeDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Graduate School of Medical Sciences, University of Groningen, Groningen, The Netherlands. n.f.van.rhee@umcg.nl.ORCID 0009-0009-0457-9439
Rosanne C SchoonbeekDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-3103-943X
Inge WegnerDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-4124-7224
Karin M VermeulenDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-9257-2791
Robert C MaatDepartment of Otorhinolaryngology, Saxenburgh Medical Center, Hardenberg, The Netherlands.
Dirk A Dietz de LoosDepartment of Otorhinolaryngology, Isala Hospital, Zwolle, The Netherlands.
György B HalmosDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-2460-2260
Boudewijn E C PlaatDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-8631-7727

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIn the Netherlands, care for head and neck cancer (HNC) is centralised in head and neck oncology centres (HNOCs). Follow-up after treatment requires frequent visits that can burden patients and providers. Telemedicine, through remote evaluation of laryngopharyngoscopy videos recorded at local hospitals, may offer a feasible alternative. This study protocol describes the aim to assess patient satisfaction and safety with telemedicine follow-up after treatment of (pre-)malignant glottic lesions, including severe dysplasia, carcinoma-in-situ and T1 squamous cell carcinoma, conducted at one HNOC and participating general hospitals. METHODS AND ANALYSIS: As a non-blinded, randomised controlled trial, 90 patients with a one-way travel time by car of over 45 min to the HNOC will be allocated to the intervention group (follow-up by an Ear, Nose and Throat surgeon at a nearby participating hospital) or the control group (standard follow-up at the HNOC). All patients undergo guideline-based care. In the intervention group, laryngopharyngoscopy recordings will be remotely reviewed by HNOC specialists on the same day. Surveys will be fulfilled at baseline, 6 and 12 months. The primary outcome is overall patient satisfaction using a 0-10 numeric rating scale at 12 months follow-up. Secondary outcomes are safety, quality of life, fear of recurrence, travel time and carbon-dioxide emission. Safety will be assessed through recurrence, complications, re-referral and survival. Between-group and within-group comparisons will be performed to evaluate differences in outcomes, using appropriate statistical methods based on data distribution. ETHICS AND DISSEMINATION: This study explores regional collaboration and sustainable follow-up for HNC patients. The ethics board approved the protocol (M23.325004). The authors commit to publishing the findings.

Indexed as

GlottisLaryngeal NeoplasmsPrecancerous ConditionsStandard of CareTelemedicineAftercareFemaleHumansLaryngoscopyMaleNetherlandsPatient SatisfactionQuality of LifeRandomized Controlled Trials as Topic

Identifiers

PMID40791158
PMCPMC13064437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.