Latest developments in the detection and quantification of adrenaline: advances and clinical applications.

Tijana Mutić, Aleksandar Mijajlović, Vesna Stanković, Sladjana Djurdjić, Filip Vlahović, Dalibor Stanković

Abstract readReview

In one paragraph

Review in Bioanalysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tijana MutićDepartment of Chemistry, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.

Aleksandar MijajlovićDepartment of Analytical Chemistry, Faculty of Chemistry, University of Belgrade, Belgrade, Serbia.

Vesna StankovićDepartment of Chemistry, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.

Sladjana DjurdjićDepartment of Analytical Chemistry, Faculty of Chemistry, University of Belgrade, Belgrade, Serbia.

Filip VlahovićDepartment of Chemistry, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.

Dalibor StankovićDepartment of Analytical Chemistry, Faculty of Chemistry, University of Belgrade, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenaline, a critical biomarker of stress and autonomic nervous system function, plays a central role in diagnosing and monitoring several medical conditions such as cardiovascular ailments, endocrine illnesses, and neurodegenerative syndromes. Traditional detection methods, including gas chromatography, high-performance liquid chromatography, mass spectrometry, and spectrophotometry, offer high sensitivity and specificity but are limited by complex instrumentation, high cost, and the need for specialized personnel. These constraints hinder their use in rapid, point-of-care, or decentralized settings. This review provides a thorough summary of conventional and emerging adrenaline detection technologies, focusing on recent biosensing platform advancements. Electrochemical and optical sensors enhanced by nanomaterial-based electrode modifications and advanced molecular recognition strategies have improved sensitivity, selectivity, and portability.

Indexed as

Biosensing TechniquesEpinephrineElectrochemical TechniquesHumansEpinephrineAdrenalineemerging sensing technologiesEpinephrinesensorstraditional analytical methods

Identifiers

PMID40791142

DOI10.1080/17576180.2025.2546283

PMCPMC12369626

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.