Evidence map›Paper›PMID 40790924›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2025

Automated analysis of the American Academy of Sleep Medicine Inter-Scorer Reliability gold-standard polysomnogram dataset.

Ayush Tripathi, Samaneh Nasiri, Wolfgang Ganglberger, Thijs Nassi, Erik-Jan Meulenbrugge, Haoqi Sun, Katie L Stone, Emmanuel Mignot, Dennis Hwang, Lynn Marie Trotti and 5 more

Abstract readComparative Study
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Performance of nine large language models on real-world polysomnography interpretation for obstructive sleep apnea: a multi-dimensional comparative analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ayush TripathiDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Samaneh NasiriDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Wolfgang GanglbergerDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Thijs NassiDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Erik-Jan MeulenbruggeDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Haoqi SunDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Katie L StoneDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Emmanuel MignotStanford University, Palo Alto, California.
Dennis HwangKaiser Permanente San Bernardino County Sleep Disorders Center, San Bernardino, California.
Lynn Marie TrottiDepartment of Neurology and Emory Sleep Center, Emory University School of Medicine, Atlanta, Georgia.
Matthew A ReynaDepartment of Biomedical Informatics, Emory School of Medicine, Atlanta, Georgia.
Gari D CliffordDepartment of Biomedical Informatics, Emory School of Medicine, Atlanta, Georgia.
Umakanth KatwaHarvard Medical School, Boston, Massachusetts.
Robert J ThomasHarvard Medical School, Boston, Massachusetts.
M Brandon WestoverDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

Funding

Late-onset Unexplained Epilepsy as a Risk Factor for DementiaR01NS130119 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Alice D Lam · 2023 to 2026
$8.7M
Data-Driven Sleep Biomarkers of Brain Health, Heart Health, and MortalityR01HL161253 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI CLIFFORD, GARI DAVID, MIGNOT, EMMANUEL J · 2022 to 2025
$8.3M
Comparative Safety of Seizure Prophylaxis within the Medicare ProgramR01AG073410 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Lidia Maria Veras Rocha de Moura · 2021 to 2026
$4.1M
Low Neurophysiologic Resistance to Anesthetics as a Marker of Preclinical/Prodromal Alzheimer's Disease and Neurovascular Pathology, Delirium risk and InattentionR01AG073598 · NIA · STANFORD UNIVERSITY · PI Miles Berger · 2022 to 2026
$3.8M
Integrative Motor Activity Biomarker for the Risk of Alzheimer's RiskRF1AG064312 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2019 to 2019
$3.6M
Prospective Validation of Neurophysiologic Outcome Prediction in Acute Brain InjuryR01NS126282 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Aaron F Struck, Michael Brandon Westover · 2023 to 2026
$2.9M
Establishing a Brain Health Index from the Sleep ElectroencephalogramRF1NS120947 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CASH, SYDNEY S, THOMAS, ROBERT JOSEPH · 2021 to 2021
$2.4M
Comparative Effectiveness of EEG-Guided Anti-Seizure Treatment in Acute Brain InjuryR01NS131347 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Sahar F Zafar · 2024 to 2026
$1.9M
NHLBI NIH HHS R01 HL161253NIA NIH HHS R01 AG073410NIA NIH HHS R01 AG073598NIA NIH HHS RF1 AG064312NINDS NIH HHS R01 NS126282NINDS NIH HHS R01 NS130119NINDS NIH HHS R01 NS131347NINDS NIH HHS RF1 NS120947
6 · The paper itself

Abstract

STUDY

objectivesWe compared the performance of a comprehensive automated polysomnogram analysis algorithm-CAISR (Complete Artificial Intelligence Sleep Report)-to a multiexpert gold-standard panel, crowdsourced scorers, and experienced technicians for sleep staging and detecting arousals, respiratory events, and limb movements.

methodsA benchmark dataset of 57 polysomnogram records (Inter-Scorer Reliability dataset) with 200 30-second epochs scored per American Academy of Sleep Medicine guidelines was used. Annotations were obtained from (1) the American Academy of Sleep Medicine multiexpert gold-standard panel, (2) American Academy of Sleep Medicine Inter-Scorer Reliability (ISR) platform users ("crowd," averaging 6,818 raters per epoch), (3) 3 experienced technicians, and (4) CAISR. Agreement was assessed via Cohen's kappa (κ) and percent agreement.

resultsAcross tasks, CAISR achieved performance comparable to that of experienced technicians but did not match consensus-level agreement between the multiexpert gold standard and the crowd. For sleep staging, CAISR's agreement with multiexpert gold standard was 82.1% (κ = 0.70), comparable to experienced technicians but below the crowd (κ = 0.88). Arousal detection showed 87.81% agreement (κ = 0.45), respiratory event detection 83.18% agreement (κ = 0.34), and limb movement detection 94.89% agreement (κ = 0.11), each aligning with performance equivalent to experienced technicians but trailing crowd agreement (κ = 0.83, 0.78, and 0.86 for detection of arousal, respiratory events, and limb movements, respectively).

conclusionsCAISR achieves experienced technician-level accuracy for polysomnogram scoring tasks but does not surpass the consensus-level agreement of a multiexpert gold standard or the crowd. These findings highlight the potential of automated scoring to match experienced technician-level performance while emphasizing the value of multirater consensus. CITATION: Tripathi A, Nasiri S, Ganglberger W, et al. Automated analysis of the American Academy of Sleep Medicine Inter-Scorer Reliability gold-standard polysomnogram dataset.

Indexed as

Artificial IntelligenceDiagnosis, Computer-AssistedPolysomnographySleep Wake DisordersConsensusDatasets as TopicHumansObserver VariationReproducibility of ResultsSleep Medicine SpecialtySocieties, MedicalUnited Statesarousal detectionartificial intelligenceinter-rater reliabilitylimb movementpolysomnographyrespiratory eventssleep staging

Identifiers

PMID40790924
PMCPMC12582208

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.