Evidence map›Paper›PMID 40790842›Full record

SynthesisPsycho-oncology2025

Effect of Cognitive Training on Cancer-Related Cognitive Impairment in Patients With Breast Cancer: A Systematic Review and Meta-Analysis.

Celia Sánchez-Gómez, Eduardo José Fernández-Rodríguez, Samuel Jiménez-Sánchez, Emilio Fonseca-Sánchez, Jesus Perez, Víctor Navarro-López, Sara Jiménez García-Tizón, Juan Luis Sánchez-González

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Celia Sánchez-GómezDepartment of Developmental and Educational Psychology, University of Salamanca, Salamanca, Spain.ORCID 0000-0002-1196-816X
Eduardo José Fernández-RodríguezInstitute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.ORCID 0000-0002-2175-8545
Samuel Jiménez-SánchezDoctoral Programme in Health, Disability, Dependence and Welfare. University of Salamanca, Salamanca, Spain.ORCID 0009-0004-0488-2300
Emilio Fonseca-SánchezInstitute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.ORCID 0000-0001-7363-6454
Jesus PerezInstitute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.ORCID 0000-0003-0740-190X
Víctor Navarro-LópezFaculty of Health Sciences, Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Madrid, Spain.ORCID 0000-0003-1362-6312
Sara Jiménez García-TizónDepartment of Developmental and Educational Psychology, University of Salamanca, Salamanca, Spain.ORCID 0000-0003-3960-8665
Juan Luis Sánchez-GonzálezInstitute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.ORCID 0000-0002-4791-6513

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer-related cognitive impairment (CRCI) associated with chemotherapy ('chemobrain') in patiens with breast cancer represents a challenging sequelae of cancer treatment. Cognitive training (CT) has shown potential to improve CRCI.

aimThis systematic review with meta-analysis aimed to evaluate the efficacy of CT in improving CRCI in patients with breast cancer.

methodsA systematic literature review was conducted in PubMed, Web of Science, Scopus, Embase, Cochrane Library, PsycInfo, CINAHL Complete, ClinicalTrials.gov and Psicodoc databases for studies published up to January 2025. Methodological quality was assessed using PRISMA, RoB 2 and the PEDro Scale. The protocol was registered in PROSPERO (CRD42025636745).

resultsOf 7751 studies identified, 11 met inclusion criteria and 9 were included in the meta-analysis. Eight studies assessed the effect of CT on the FACT-Cog scale global score, showing a significant effect (SMD = 0.2; IC del 95%: -0.39 a -0.01; p = 0.04), and low heterogeneity (I

conclusionsCT could be effective in improving CRCI in patients with breast cancer. However, the existing evidence is of low quality and, therefore, higher quality studies with larger samples are still warranted.

Indexed as

Breast NeoplasmsChemotherapy-Related Cognitive ImpairmentCognitive Behavioral TherapyCognitive DysfunctionCognitive TrainingFemaleHumansQuality of Lifebreast cancercancercancer‐related cognitive impairmentchemobraincognitive trainingmeta‐analysisoncology

Identifiers

PMID40790842
PMCPMC12340179

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.