Unusual Fragmentations of Silylated Polyfluoroalkyl Compounds Induced by Electron Ionization.

Yufang Zheng, Edward P Erisman, Weihua Ji, Stephen E Stein, William E Wallace

Abstract read

In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Frontiers in pharmacology · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yufang ZhengMass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States.ORCID 0009-0003-1336-5420

Edward P ErismanMass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States.

Weihua JiMass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States.ORCID 0009-0005-2737-8059

Stephen E SteinMass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States.ORCID 0000-0001-9384-3450

William E WallaceMass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) are environmentally persistent compounds that present analytical challenges due to their stability and low concentrations. In this study, electron ionization (EI) mass spectra of trimethylsilyl (TMS) derivatized fluorinated alcohols and carboxylic acids were examined to improve PFAS identification in the NIST Mass Spectral Reference Library. In contrast with the spectra of unsubstituted alcohol TMS compounds featuring losses of hydrocarbons, fluorinated alcohol TMS derivatives are characterized by the losses of fluorinated silyl groups. For example, a previously unreported [M-111]

Indexed as

fluorinated alcoholsfluorinated carboxylic acidsion fragmentation pathwayPFASreference libraryreference spectrum

Identifiers

PMID40790616

DOI10.1021/jasms.5c00185

PMCPMC12412168

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.