Evidence map›Paper›PMID 40790410›Full record

ReviewDermatology practical & conceptual2025

Laser Therapy Approaches in the Treatment of Kaposi's Sarcoma: A Comprehensive Review of Dermatologic Options.

Chiara Battilotti, Fortunato Cassalia, Francesca Svara, Alessandra Latini, Norma Cameli, Steven Paul Nisticò

Abstract readReview
In one paragraph

Review in Dermatology practical & conceptual, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chiara BattilottiDepartment of Dermatology, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Fortunato CassaliaUnit of Dermatology, Department of Medicine, University of Padua, Padua, Italy.
Francesca SvaraDepartment of Dermatology, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Alessandra LatiniDepartment of Dermatology, San Gallicano Dermatological Institute-IRCCS, Rome, Italy.
Norma CameliDepartment of Dermatology, San Gallicano Dermatological Institute-IRCCS, Rome, Italy.
Steven Paul NisticòDepartment of Dermatology, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKaposi's sarcoma (KS) is a multicentric angioproliferative disease associated with human herpesvirus 8 and often exacerbated by immunosuppression. Effective treatment includes systemic and local therapies, with laser treatments gaining prominence in dermatological practice.

objectivesThis narrative review evaluated the efficacy and safety of laser treatment modalities in the management of cutaneous and mucosal KS lesions to guide dermatological decision-making.

methodsA comprehensive English-language literature search was conducted using PubMed and Scopus up to November 2024. Search terms included "Kaposi's sarcoma", "laser therapy," and "laser treatment." Case reports and observational studies with defined patient characteristics, standardized laser protocols, and documented outcomes were included.

resultsThe Nd:YAG laser emerged as the leading modality for thick, nodular KS lesions, demonstrating deep tissue penetration and high efficacy with minimal adverse effects. The pulsed dye laser (PDL) was highly effective for superficial cutaneous and mucosal lesions, with excellent cosmetic outcomes and minimal recurrence. The CO

conclusionsLaser therapy offers versatile and effective treatment options for KS. Nd:YAG and PDL lasers are particularly promising due to their high efficacy, favorable safety profiles, and low recurrence rates. Further research is needed to refine laser protocols and validate long-term outcomes in different patient populations.

Identifiers

PMID40790410
PMCPMC12339106

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.