Evidence map›Paper›PMID 40790401›Full record

ReviewDermatology practical & conceptual2025

Atopic Dermatitis and Autoimmune Connective Tissue Diseases: Systematic Review and Meta-Analysis.

Somaia Naassan, Misbah Noshela Ghazanfar, Simon Francis Thomsen, Zarqa Ali

Abstract readReview
In one paragraph

Review in Dermatology practical & conceptual, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Somaia NaassanDepartment of Dermato-Venereology & Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark.
Misbah Noshela GhazanfarDepartment of Dermato-Venereology & Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark.
Simon Francis ThomsenDepartment of Dermato-Venereology & Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark.
Zarqa AliDepartment of Dermato-Venereology & Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe association between atopic dermatitis (AD) and autoimmune connective tissue diseases (ACTD) is not well investigated.

objectiveWe aimed to conduct a systematic review and meta-analysis to assess the association between AD and ACTD.

methodsA comprehensive literature search was performed on PubMed, Embase, Cochrane Library, and Web of Science to identify relevant studies, which included those providing original data on the prevalence, incidence, or risk of ACTD in people with AD. Pooled point prevalence and odds ratio (OR) with 95% confidence intervals (CI) were estimated using a random effect inverse variance method.

resultsTwenty-one studies were included in the systematic review, of which 18 were included in the meta-analysis. The pooled ORs were statistically significant overall for ACTD, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Sjögren syndrome (SS), and polymyositis (PM)/dermatomyositis (DM), but not for ankylosing spondylitis (AS) or systemic scleroderma (SSc): any ACTD 1.76 (95% CI: 1.57-1.97, I

conclusionAD is associated with a significantly increased risk of ACTD, particularly RA, SLE, SS, and PM/DM, while no significant association was observed with AS or SSc.

Identifiers

PMID40790401
PMCPMC12339128

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.