Quantitative imaging of 478-keV prompt gamma rays from Boron neutron capture reactions.

Tetsuya Mizumoto, Shotaro Komura, Atsushi Takada, Yoshinori Sakurai, Toru Tanimori

Abstract read

In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tetsuya MizumotoDevelopment department, J-BEAM, Inc, 1-7, Nakamaru, Yamadaoka, Naraha- machi, Futaba-gun, Fukushima, 979-0513, Japan. mizumoto@cr.scphys.kyoto-u.ac.jp.

Shotaro KomuraDevelopment department, J-BEAM, Inc, 1-7, Nakamaru, Yamadaoka, Naraha- machi, Futaba-gun, Fukushima, 979-0513, Japan. komura@cr.scphys.kyoto-u.ac.jp.

Atsushi TakadaDepartment of Science, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto-shi, Kyoto, 606-8502, Japan.

Yoshinori SakuraiInstitute for Integrated Radiation and Nuclear Science, Kyoto University, 2, Asashiro-nishi, Kumatori-cho, Sennan-gun, Osaka, 590-0494, Japan.

Toru TanimoriDepartment of Science, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto-shi, Kyoto, 606-8502, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accurate imaging and quantitative measurement of 478-keV prompt gamma rays are critical for advancing boron neutron capture therapy (BNCT), a promising cancer treatment. Although numerical simulations have indicated that such measurements are feasible, their practical application has proven challenging. This study introduces a gamma-ray imaging detector designed specifically for precise BNCT measurements. Using boron-rich phantom samples, we successfully imaged 478-keV gamma rays and established a linear correlation between gamma-ray production and boron concentration. Furthermore, applying this technique in a recognized BNCT treatment facility demonstrated the detector's effectiveness in monitoring boron dose distribution during neutron irradiation, both in pre-treatment diagnostics and throughout the treatment process.

Identifiers

PMID40790331

DOI10.1038/s41598-025-14212-8

PMCPMC12339688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.