Evidence map›Paper›PMID 40790324›Full record

ArticleScientific reports2025

Transcriptomic profiling of skeletal muscle in the DMD

Abdolvahab Ebrahimpour Gorji, Katarzyna Kliczkowska, Marcin Ollik, Caroline Le Guiner, Jacek Wilczak, Wojciech Bielecki, Piotr Ostaszewski, Masoud Shirali, Zahra Roudbari, Tomasz Sadkowski

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abdolvahab Ebrahimpour GorjiDepartment of Physiological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, 02-776, Poland.
Katarzyna KliczkowskaDepartment of Pathology and Veterinary Diagnostics, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, 02-776, Poland.
Marcin OllikDepartment of Biometry, Institute of Agriculture, Warsaw University of Life Sciences, Warsaw, 02-776, Poland.
Caroline Le GuinerTranslational Gene Therapy Laboratory (TaRGeT), Nantes Université, CHU de Nantes, INSERM UMR 1089, Nantes, France.
Jacek WilczakDepartment of Physiological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, 02-776, Poland.
Wojciech BieleckiDepartment of Pathology and Veterinary Diagnostics, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, 02-776, Poland.
Piotr OstaszewskiDepartment of Physiological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, 02-776, Poland.
Masoud ShiraliSchool of Biological Sciences, Queen's University Belfast, Belfast, BT9 5DL, UK.
Zahra RoudbariDepartment of Animal Science, Faculty of Agriculture, University of Jiroft, Jiroft, Iran.
Tomasz SadkowskiDepartment of Physiological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, 02-776, Poland. tomasz_sadkowski@sggw.edu.pl.

Funding

Narodowe Centrum Nauki 2020/37/B/N25/01744
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a severe X-linked recessive disorder caused by a mutation in the Dmd gene, leading to progressive muscle degradation, increasing weakness, and typically resulting in death before the third decade of life. To investigate the pathobiology of DMD, this study employed the Sprague-Dawley Dmd-mutated rat model (DMD

Indexed as

DystrophinGene Expression ProfilingMuscle, SkeletalMuscular Dystrophy, DuchenneTranscriptomeAnimalsDisease Models, AnimalMaleRatsRats, Sprague-DawleyDystrophinDuchenne muscular dystrophy (DMD)Dystrophin gene mutationMAPK signaling pathway, DMD mdx rat modelRNA-seq gene expression analysisSkeletal muscle degeneration

Identifiers

PMID40790324
PMCPMC12340039

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.