Evidence map›Paper›PMID 40790115›Full record

ArticleNature communications2025

Cross-membrane cooperation among bacteria can facilitate intracellular pathogenesis.

Daniel Schator, Naren G Kumar, Samuel Joseph U Chong, Timothy K Jung, Eric Jedel, Benjamin E Smith, David J Evans, Suzanne M J Fleiszig

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Daniel SchatorHerbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-6741-6527
Naren G KumarHerbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-7248-6351
Samuel Joseph U ChongHerbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, CA, USA.
Timothy K JungHerbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, CA, USA.
Eric JedelHerbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, CA, USA.
Benjamin E SmithHerbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, CA, USA.
David J EvansHerbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-6885-2053
Suzanne M J FleiszigHerbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, CA, USA. fleiszig@berkeley.edu.ORCID http://orcid.org/0000-0001-6324-3462

Funding

UC Berkeley Vision Science COREP30EY003176 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI RICHARD H KRAMER · 1985 to 2026
$16.4M
SIGNIFICANCE OF CORNEAL CELL INVASION BY BACTERIAR01EY011221 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Suzanne MJ FLEISZIG · 1995 to 2026
$8.4M
NEI NIH HHS P30 EY003176NEI NIH HHS R01 EY011221U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) P30EY003176U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) R01EY011221
6 · The paper itself

Abstract

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen able to cause life- and sight-threatening infections. Once considered an extracellular pathogen, numerous studies have shown it can survive intracellularly. Previously, we showed that P. aeruginosa inside cells can diversify into distinct subpopulations in vacuoles and the cytoplasm. Here, we report that the transition from vacuoles to cytoplasm requires collaboration with the extracellular subpopulation, through Ca

Indexed as

Cell MembranePseudomonas aeruginosaPseudomonas InfectionsAnimalsBacterial ProteinsCalciumCytoplasmDisease Models, AnimalFemaleHumansMiceType III Secretion SystemsVacuolesBacterial ProteinsCalciumType III Secretion Systems

Identifiers

PMID40790115
PMCPMC12339937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.