SynthesisJournal of robotic surgery2025
Comparative outcomes of holmium laser enucleation of the prostate (HoLEP) versus robotic-assisted simple prostatectomy (RASP) for benign prostatic hyperplasia: a systematic review and meta-analysis.
Synthesis in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Robot-assisted simple prostatectomy vs. laser enucleation of the prostate for large-volume benign prostatic hyperplasia (BPH, ≥80 mL): a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Comparative efficacy and safety of robotic-assisted versus open retroperitoneal lymph node dissection in testicular cancer management: a systematic review and meta-analysis.Journal of robotic surgery · 2025Pooled it
- Suprapubic transvesical adenoma resection versus robot-assisted simple prostatectomy for prostates ≥ 80 mL: an exploratory early-outcome comparison.World journal of urology · 2026Article
- Robot-Assisted Simple Prostatectomy Versus Endoscopic Enucleation for Large-Volume Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis of Perioperative Outcomes and Complications.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
With the rising prevalence of benign prostatic hyperplasia (BPH), there is an increasing demand for surgical interventions that optimize patient outcomes while minimizing complications. This systematic review aims to critically evaluate and contrast the clinical outcomes, surgical efficiency, and safety profiles during the perioperative period for holmium laser enucleation of the prostate (HoLEP) and robot-assisted simple prostatectomy (RASP) in patients diagnosed with BPH exhibiting a prostate volume of ≥ 80 mL, providing evidence-based insights for BPH management. Adhering to the EAU Guidelines Office and PRISMA guidelines, the study protocol was registered with Prospero [CRD420251059418]. A comprehensive literature search was conducted in Web of Science, Embase, PubMed and Scopus up to May 10, 2025, to identify comparative studies of HoLEP and RASP in BPH patients. The methodological quality of the included studies was systematically evaluated using the Newcastle-Ottawa Scale (NOS), a validated tool specifically designed to assess the risk of bias in observational studies. Eleven studies involving 1772 patients (1247 HoLEP; 525 RASP) met inclusion criteria. Both techniques demonstrated comparable efficacy in functional outcomes, including maximum urinary flow rate, post-void residual volume, International Prostate Symptom Score (IPSS), and quality of life (QoL). However, HoLEP exhibited superior efficiency metrics: Reduced estimated blood loss: 105.01 mL (p < 0.005); Shorter catheterization time: 4.36 days (p < 0.00001); Lower transfusion risk: 32% reduction (p = 0.02). Operative time and postoperative complications showed no significant differences between groups. HoLEP and RASP are equally effective for managing large prostates. HoLEP offers advantages in minimizing blood loss, catheter duration, and transfusion rates, while RASP benefits from procedural ease in robotic-equipped facilities. Optimizing outcomes requires addressing disparities in technique adoption, enhancing surgical training, and aligning with evidence-based guidelines. Future high-quality randomized trials are warranted to refine personalized decision-making for clinicians and patients.
Indexed as
Identifiers
40790006What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.