ArticleMikrochimica acta2025
Rational design and in vivo toxicity assessment of multichannel fluorescent carbon dots derived from Withania coagulans in Drosophila melanogaster.
Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Carbon Dots in Nanomedicine: Advanced Fabrication, Biomedical Applications, and Future Clinical Perspectives.Pharmaceutics · 2026Review
- Exploring Carbon Dot Nanoparticles for Imaging and Cellular Interaction in Triple-Negative Breast Cancer.International journal of nanomedicine · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
In vivo imaging with biocompatible fluorescent agents such as carbon dots (C-Dots) is becoming increasingly popular in theranostics. This study investigates the efficacy and safety of fluorescent C-Dots derived from Withania coagulans (WC) flowers, as well as their modified version, through in vitro and in vivo experiments. A hydrothermal method was used to synthesize three types of C-Dots, i.e. WC-CD, WC-Cys-CD, and WC-FA-CD, using WC flowers alone and with cysteamine (Cys) and folic acid (FA) respectively. We observed that the surface-modified carbon dots exhibited higher fluorescence quantum yields of 2.13 and 7.27% for WC-Cys-CD and WC-FA-CD compared with unmodified ones (WC-CD; 0.68%). The surface analysis and optical profile confirm the formation of CDs having the crystalline core composed of sp
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