Evidence map›Paper›PMID 40789871›Full record

ArticleScientific reports2025

Oral respiration modulates sensory and cognitive brain potentials differently than nasal respiration.

Viviana Leupin, Juliane Britz

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Viviana LeupinDepartment of Psychology, University of Fribourg, University of Fribourg, Rue P.-A. Faucigny 2, Fribourg, CH-1700, Switzerland.
Juliane BritzDepartment of Psychology, University of Fribourg, University of Fribourg, Rue P.-A. Faucigny 2, Fribourg, CH-1700, Switzerland. juliane.britz@unifr.ch.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 10001C_ 189408
6 · The paper itself

Abstract

Respiration influences brain activity and awareness through two mechanisms: direct rhythmic entrainment via olfactory bulb (OB) stimulation and indirect modulation through baroreceptor (BR) activity fluctuations that affect cortical excitability. During nasal breathing, both mechanisms are active and can influence sensory event-related potentials (ERPs). To isolate the contribution of BR activity, we tested the same paradigm during oral breathing, which eliminates OB stimulation. Results showed that sensory ERPs varied with the cardiac (with delayed timing) but not with the respiratory phase. The P3a component was modulated by awareness only when BR activity was low (during inhalation and diastole), while the visual awareness negativity (VAN) and P3b were modulated by awareness across all conditions. These findings indicate that BR fluctuations alone cannot fully account for the respiratory modulation of awareness-related ERPs, but they require entrainment of brain activity modulated by mechanical OB stimulation.

Indexed as

BrainCognitionEvoked PotentialsRespirationAdultAwarenessElectroencephalographyFemaleHumansMaleOlfactory BulbYoung AdultBrain–body interactionConsciousnessEEGOral breathingRespiratory phase

Identifiers

PMID40789871
PMCPMC12340021

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.