Evidence map›Paper›PMID 40789333›Full record

ArticleJornal de pediatria

Associations between adverse childhood experiences and perinatal outcomes.

Nina de Siqueira Kuperman, Maria Clara Magalhães-Barbosa, Fernanda de Carvalho Lima, Mariana Barros Genuino de Oliveira, Jaqueline Rodrigues Robaina, Margarida Dos Santos Salú, Arnaldo Prata-Barbosa, Antônio José Ledo Alves da Cunha

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Article in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Nina de Siqueira KupermanUniversidade Federal do Rio de Janeiro (UFRJ), Faculdade de Medicina, Programa de Pós-Graduação em Medicina Interna, Rio de Janeiro, RJ, Brazil. Electronic address: arnaldo.prata@idor.org.
Maria Clara Magalhães-BarbosaInstituto D'Or de Pesquisa e Ensino (IDOR), Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.
Fernanda de Carvalho LimaInstituto D'Or de Pesquisa e Ensino (IDOR), Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.
Mariana Barros Genuino de OliveiraInstituto D'Or de Pesquisa e Ensino (IDOR), Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.
Jaqueline Rodrigues RobainaInstituto D'Or de Pesquisa e Ensino (IDOR), Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.
Margarida Dos Santos SalúInstituto D'Or de Pesquisa e Ensino (IDOR), Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.
Arnaldo Prata-BarbosaUniversidade Federal do Rio de Janeiro (UFRJ), Faculdade de Medicina, Programa de Pós-Graduação em Medicina Interna, Rio de Janeiro, RJ, Brazil; Instituto D'Or de Pesquisa e Ensino (IDOR), Departamento de Pediatria, Rio de Janeiro, RJ, Brazil; Universidade Federal do Rio de Janeiro (UFRJ), Faculdade de Medicina, Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.
Antônio José Ledo Alves da CunhaUniversidade Federal do Rio de Janeiro (UFRJ), Faculdade de Medicina, Programa de Pós-Graduação em Medicina Interna, Rio de Janeiro, RJ, Brazil; Instituto D'Or de Pesquisa e Ensino (IDOR), Departamento de Pediatria, Rio de Janeiro, RJ, Brazil; Universidade Federal do Rio de Janeiro (UFRJ), Faculdade de Medicina, Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the frequency of adverse childhood experiences (ACE) among a cohort of pregnant women (primary outcome) and explore their association with prematurity, pre-eclampsia, and fetal growth restriction (secondary outcomes).

methodsThe Adverse Childhood Experiences International Questionnaire - ACE-IQ was applied to patients during prenatal visits. Information on perinatal outcomes was collected from medical records. The proportion of total ACE and its different domains was estimated. Multiple logistic regressions were performed to assess the association between ACE and outcomes, after adjusting for possible confounding factors.

resultsA cohort of 307 pregnant women completed the ACE-IQ. The results in the binary and frequency versions were, respectively: mean (SD) scores of 5.84 (2.87) and 3.55 (2.73); the proportion of ACE 4 of 75% and 44%; the most prevalent ACE domains were home dysfunction (89.6 and 86.6%) and exposure to community violence (76.5 and 50%). For fetal growth restriction, pregnant women with ACE ≥ 4 had 2.32 times (95% CI: 1.04-5.37; p = 0.042) higher chance of this outcome. For preterm birth, the odds ratio was 1.1 (95% CI: 0.5-2.6; p = 0.886), indicating no statistically significant association. There was no significant association between the total ACE score, or its domains, and the other perinatal outcomes studied.

conclusionsThe frequency of ACE was high in this cohort of pregnant women, and exposure to community violence was associated with fetal growth restriction. The investigation of the association with other perinatal outcomes should be extended to a general population of pregnant women.

Indexed as

Adverse Childhood ExperiencesFetal Growth RetardationPre-EclampsiaPremature BirthAdultFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeRisk FactorsSurveys and QuestionnairesYoung AdultACE-IQAdverse experiences in childhoodChild abuse and neglectGestational outcomes

Identifiers

PMID40789333
PMCPMC12744608

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.