Evidence map›Paper›PMID 40789218›Full record

ArticleJournal of neurosurgery. Case lessons2025

Intracranial multiple myeloma masquerading as subdural hematoma: illustrative cases.

Stephanie A Ihezie, Vishva Natarajan, George Zanazzi, Swaroopa PonnamReddy, Fredrick Lansigan, Linton T Evans, Jennifer Hong

Abstract read
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie A IhezieDepartment of Surgery, Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Vishva NatarajanDepartment of Surgery, Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.ORCID 0009-0008-0647-7826
George ZanazziDepartment of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Swaroopa PonnamReddyDartmouth Cancer Center, Section of Hematology/Oncology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Fredrick LansiganDartmouth Cancer Center, Section of Hematology/Oncology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Linton T EvansDepartment of Surgery, Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Jennifer HongDepartment of Surgery, Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.

Funding

Zhao - Proj 2P20GM130454 · NIGMS · DARTMOUTH COLLEGE · PI Li Song · 2019 to 2026
$27.2M
NIGMS NIH HHS P20 GM130454
6 · The paper itself

Abstract

backgroundIntracranial involvement in multiple myeloma (MM) is a rare clinical presentation, often mimicking other conditions such as subdural hematoma (SDH) and resulting in poor prognosis. OBSERVATIONS: This case series highlights 2 older female patients, one with a prior diagnosis of MM, who developed subdural masses resembling SDH. Both cases were associated with significant cerebral edema and mass effect. Biopsies confirmed plasma cell neoplasms, and both patients underwent tailored treatment, including corticosteroids, radiation therapy, and systemic chemotherapy. The patients showed clinical and radiographic improvement posttreatment. LESSONS: These cases underscore the importance of maintaining a broad differential in patients with subdural collections, particularly if associated with significant vasogenic edema or in those with a history of MM. Nonoperative management is effective, despite mass effect. https://thejns.org/doi/10.3171/CASE25347.

Indexed as

central nervous systemmultiple myelomaplasmacytomaradiationsubdural

Identifiers

PMID40789218
PMCPMC12337981

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.