ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Transcriptome-Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- A copy-number variation generates a long-noncoding RNA that enhances ClBige1b expression to suppress cell expansion and seed growth in watermelon.Plant communications · 2026Article
- Genome-Wide Characterization of Long Non-Coding RNAs Identifies Candidate Regulatory Networks During Modern Maize Breeding.Plants (Basel, Switzerland) · 2026Article
- Transcriptome-Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Long non-coding RNAs (lncRNAs) are emerging as key regulators of various biological processes in plants, yet their role in seed weight regulation remains underexplored. To systematically investigate lncRNAs associated with seed weight variation, transcriptome-wide association studies (TWAS) are performed across a diversity panel of 238 soybean accessions. The analysis identifies 175 and 50 TWAS-significant lncRNAs at 14 and 21 days after flowering, respectively. Functional validation reveals that two candidate lncRNAs positively regulate seed weight through transcriptional modulation of key genes in seed development pathways. Additionally, an lncRNA-lncRNA co-expression module is identified as significantly correlated with seed weight. The eQTL analysis reveals dynamic and static eQTLs that coordinately modulate lncRNA expression across seed developmental stages. Notably, integration of major-effect proximal and minor-effect distal eQTLs enhances phenotype prediction of seed weight, underscoring the significant impact of distal eQTLs on phenotypic variation. These findings elucidate the intricate mechanisms by which lncRNAs contribute to seed weight regulation, offering novel insights for enhancing crop yield.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.