Evidence map›Paper›PMID 40788975›Full record

ArticleCirculation2025

Novel Human Heart-Derived Natural Adeno-Associated Virus Capsid Combines Cardiospecificity With Cardiotropism In Vivo.

Daniel Zeissler, Martin Busch, Sebastian Grieskamp, Eric Meinhardt, Hanna Wurzer, Shubhada R Kulkarni, Anna K Schrattel, Stephanie Molter, Dorothea Kehr, Maria Qatato and 16 more

Abstract readLetter
In one paragraph

Article in Circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Mechanisms and Therapeutic Potential of Human Cardiomyocyte Proliferation.Journal of cardiovascular development and disease · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Daniel Zeissler *Division of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.
Martin Busch *Division of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0002-2717-7063
Sebastian GrieskampDivision of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0009-0002-1076-6707
Eric MeinhardtDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0001-8013-4225
Hanna WurzerDivision of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.
Shubhada R KulkarniDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0003-2290-8004
Anna K SchrattelDivision of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0009-0009-1884-3392
Stephanie MolterDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.
Dorothea KehrDivision of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.
Maria QatatoDivision of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.
Christoph RummelInstitute of Veterinary Physiology and Biochemistry, Justus-Liebig University Giessen, Germany (C.R.).ORCID 0000-0001-5457-4390
Arne HansenInstitute of Experimental Pharmacology and Toxicology, University Hospital Hamburg-Eppendorf, Hamburg, Germany (A.H., M.L., K.M.W.).
Malte LoosInstitute of Experimental Pharmacology and Toxicology, University Hospital Hamburg-Eppendorf, Hamburg, Germany (A.H., M.L., K.M.W.).ORCID 0000-0001-7227-0147
Kinga M WronaInstitute of Experimental Pharmacology and Toxicology, University Hospital Hamburg-Eppendorf, Hamburg, Germany (A.H., M.L., K.M.W.).ORCID 0000-0002-5123-2990
Mirko VölkersDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0003-2344-1856
Vivien KmietczykDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.
Julia WingertDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.
Viet Loan Dao ThiDepartment of Infectious Diseases, Medical Faculty Heidelberg, Heidelberg University, Germany (V.L.D.T., J.H.).ORCID 0000-0003-2293-3592
Jungen HuDepartment of Infectious Diseases, Medical Faculty Heidelberg, Heidelberg University, Germany (V.L.D.T., J.H.).
Philipp SchlegelDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0003-3888-6655
Christoph DieterichDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0001-9468-6311
Hugo A KatusDeutsches Zentrum für Herz- und Kreislaufforschung, Partner Site Heidelberg/Mannheim, Heidelberg, Germany (M.B., E.M., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., H.A.K., N.F., J.R., P.M.).ORCID 0000-0002-2293-2314
Norbert FreyDepartment of Internal Medicine III (D.Z., M.B., S.G., E.M., H.W., S.R.K., A.K.S., S.M., D.K., M.Q., M.V., V.K., J.W., P.S., C.D., N.F., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0001-7611-378X
Andreas JungmannDivision of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.
Julia Ritterhoff *Division of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0002-3419-4830
Patrick Most *Division of Molecular and Translational Cardiology (D.Z., M.B., S.G., H.W., A.K.S., D.K., M.Q., A.J., J.R., P.M.), University Hospital Heidelberg, Germany.ORCID 0000-0002-3604-2419

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adeno-associated virusgene therapyheart failure

Identifiers

PMID40788975
PMCPMC12333510

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