Evidence map›Paper›PMID 40788667›Full record

ArticleThe Journal of general virology2025

Optimum level of NEDD4 and its interaction with nsP3 are crucial to facilitate efficient Chikungunya virus (CHIKV) infection.

Suchanda Verma, Sanchari Chatterjee, Supriya Suman Keshry, Ajit Kumar Dhal, Bijita Bhowmick, Janu Newar, Soma Chattopadhyay, Archana Ghatak

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Suchanda VermaSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, India.
Sanchari ChatterjeeInstitute of Life Sciences, Bhubaneswar, India.
Supriya Suman KeshrySchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, India.
Ajit Kumar DhalSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, India.
Bijita BhowmickInstitute of Life Sciences, Bhubaneswar, India.
Janu NewarSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, India.
Soma ChattopadhyayInstitute of Life Sciences, Bhubaneswar, India.
Archana GhatakSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya is a febrile infection caused by the Chikungunya virus (CHIKV), an alphavirus which has emerged as a serious public health problem globally. Despite extensive research, our understanding of different host factors facilitating effective CHIKV infection is not clear yet. NEDD4, a member of the E3 ubiquitin ligase, is one such protein. Here, the importance of NEDD4 has been explored during CHIKV infection

Indexed as

Chikungunya FeverChikungunya virusHost-Pathogen InteractionsNedd4 Ubiquitin Protein LigasesViral Nonstructural ProteinsAnimalsCell LineHEK293 CellsHumansProtein BindingViral LoadNedd4 protein, humanNedd4 Ubiquitin Protein Ligasesnsp3 protein, alphavirusViral Nonstructural ProteinsChikungunyahost proteininfectioninteractionNEDD4

Identifiers

PMID40788667
PMCPMC12451614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.