Trial reportOral and maxillofacial surgery2025
Comparative evaluation of V-Loc knotless closure system and silk sutures in impacted mandibular third molar surgery: a split-mouth randomized controlled trial.
Trial report in Oral and maxillofacial surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
purposeSutures are the most frequently utilized to ensure a watertight seal, reposition the flap to its natural alignment, provide mechanical stability to secure tissues during the early healing phase, and reduce the risk of postoperative complications. This study aimed to evaluate and compare the effectiveness of the V-Loc Poly (p-dioxanone) knotless Tissue Control Device wound closure system and conventional silk suture in intra-oral closure following surgical removal of impacted mandibular third molar.
methodsThis is a prospective randomized split-mouth study involving 17 patients with bilateral mirror image third molars, one side received V- Loc unidirectional knotless barbed sutures while the other received silk sutures for the study and control group on a week's interval accordingly. The primary outcome parameter measured was wound closure time. Secondary outcome parameters measured were mouth opening, swelling, wound healing (Landry's index), and pain. The secondary outcome parameters were assessed on the 3rd, 5th, 7th, and 14th postoperative days.
resultsThe closure time showed a statistically significant difference, with an average time difference of 1.3 min. Additionally, wound healing was significantly different between the study and control groups on postoperative day 3 (p = 0.019) and day 14 (p < 0.001).
conclusionThis absorbable knotless suture promotes efficient wound healing and prevents postoperative complications like infections or dry socket. The time taken for the closure of the socket is longer when a knotless suture is placed, though this technique has a learning curve that is generally short to moderate, which takes an average of 3-5 cases for the clinicians to adapt, and with a brief demonstration or by watching a technique video.
trial registrationClinical Trial Registry, India, (ICMRNIMS) (registration No CTRI/2024/04/065383).
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