Evidence map›Paper›PMID 40788458›Full record

ArticleAdvances in therapy2025

COVID-19-Related Healthcare Resource Utilisation and Costs in Paediatric Patients in Germany: A Population-Based Study.

Kiran K Rai, Hannah Gowman, Monica Seif, Lucy Massey, Hannah Volkman, Andrea Schmetz, Jennifer Nguyen, Jingyan Yang

Abstract read
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Article in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kiran K RaiAdelphi Real World, Bollington, UK.
Hannah GowmanAdelphi Real World, Bollington, UK.
Monica SeifAdelphi Real World, Bollington, UK.
Lucy MasseyAdelphi Real World, Bollington, UK.
Hannah VolkmanPfizer Inc., 66 Hudson Blvd E, New York, NY, 10001, USA.
Andrea SchmetzBioNTech Europe GmbH, Berlin, Germany.
Jennifer NguyenPfizer Inc., 66 Hudson Blvd E, New York, NY, 10001, USA.
Jingyan YangPfizer Inc., 66 Hudson Blvd E, New York, NY, 10001, USA. Jingyan.Yang@pfizer.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is limited evidence on the economic burden of COVID-19 in Germany. This study aims to quantify healthcare resource utilisation (HCRU) and direct medical costs associated with COVID-19 in paediatrics in Germany.

methodsThis was a population-based retrospective cohort study using data from the German Statutory Health Insurance (SHI) claims database to define outpatient (April 2020 to December 2021) and hospitalised (April 2020 to October 2022) cohorts of paediatric patients (aged 1-17 years) with a COVID-19 diagnosis.

resultsIn the outpatient cohort (n = 104,656), most (77%) patients had ≥ 2 COVID-19-related general practitioner (GP) visits and 29% had ≥ 1 specialist visit during their diagnosis quarter. Outpatient resource use was greater in high-risk patients. When stratified by age, a greater proportion of children aged 1-4 years had ≥ 2 GP consultations, with specialist visits more common in those aged 5-11 years. The median cost per COVID-19 diagnosis quarter per patient was €192. Among the hospitalised cohort (n = 3129), the median general inpatient length of hospital stay (LoS) per patient per admission was 6.0 days; LoS was highest in those aged 5-11 years (7.0 days), at high risk (7.0 days) and during Alpha and Omicron predominance (both 7.0 days). The median cost per admission per patient was €12,503. Admission to critical care was observed in 13%, in whom the median cost per hospitalisation was €21,193.

conclusionsCOVID-19-associated HCRU and costs among the paediatric population in Germany are non-negligible, driven largely by hospitalisations, particularly those who had a critical care admission and were at high risk.

Indexed as

COVID-19Health Care CostsPatient Acceptance of Health CareAdolescentChildChild, PreschoolFemaleGermanyHealth ResourcesHospitalizationHumansInfantLength of StayMaleRetrospective StudiesSARS-CoV-2CostsCOVID-19HospitalisationPaediatricsPrimary careSecondary care

Identifiers

PMID40788458
PMCPMC12474641

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.