Evidence map›Paper›PMID 40788366›Full record

ReviewArchives of microbiology2025

Recent advances of muconic acid production using microbial synthetic biology.

Xiqiang Liu, Jintao Lu, Siqi Chen, Mingyang Wang, Aamer Ali Shah, Chunjie Gong

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiqiang LiuKey Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education and Hubei Province), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, 430068, People's Republic of China.
Jintao LuKey Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education and Hubei Province), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, 430068, People's Republic of China.
Siqi ChenKey Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education and Hubei Province), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, 430068, People's Republic of China.
Mingyang WangKey Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education and Hubei Province), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, 430068, People's Republic of China.
Aamer Ali ShahDepartment of Microbiology, Faculty of Biological Sciences, Quaid-i-Azam University, lslamabad, 45320, Pakistan.
Chunjie GongKey Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education and Hubei Province), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, 430068, People's Republic of China. gongcj606@163.com.

Funding

National Natural Science Foundation of China 32070107Undergraduate Innovation and Entrepreneurship Project of Hubei Province, China S202510500073
6 · The paper itself

Abstract

Muconic acid is a high-value intermediate with unique properties. Traditional methods for muconic acid production showed some disadvantages including expensive raw materials, environmentally sensitive, and high concentration of heavy metal catalysts. With the development of synthetic biology, bio-strategies for muconic acid production have been widely studied. In this paper, key advances in muconic acid production using synthetic biology are highlighted. Furthermore, strategies for improving muconic acid production have been discussed, including cofactor engineering, modular co-culture, and artificial intelligence-assisted enzyme optimization. Given the significant advantages of biosynthesis in clean production and cost control, the paper concludes with an analysis of the economic and technical feasibility of microbial muconic acid production.

Indexed as

BacteriaMetabolic EngineeringSorbic AcidSynthetic Biologymuconic acidSorbic AcidMetabolic engineeringMuconic acidProductionSynthesis biology

Identifiers

PMID40788366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.