Evidence map›Paper›PMID 40788229›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2024

Brief Report: Interest in Long-acting Injectable PrEP Among Transgender Women in Eastern and Southern United States.

Erin E Cooney, Sari L Reisner, Tonia C Poteat, Keri N Althoff, Asa Radix, Meg Stevenson, Andrew J Wawrzyniak, Christopher Cannon, Jason S Schneider, Kenneth H Mayer and 6 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Erin E CooneyDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.ORCID 0000-0001-9563-1822
Sari L ReisnerDepartment of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, MA.
Tonia C PoteatDivision of Healthcare in Adult Populations, Duke University School of Nursing, Durham, NC.
Keri N AlthoffDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Asa RadixCallen-Lorde Community Health Center, New York, NY.
Meg StevensonDepartment of Epidemiology, Center for Public Health and Human Rights, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Andrew J WawrzyniakDepartment of Epidemiology, Columbia University, New York, NY.
Christopher CannonDepartment of Psychiatry and Behavioral Sciences, University of Miller School of Medicine, Miami, FL.
Jason S SchneiderWhitman-Walker Institute, Washington, DC.
Kenneth H MayerDepartment of Medicine, Emory University School of Medicine, Atlanta, GA.
Chris BeyrerThe Fenway Institute, Fenway Health, Boston, MA.
Carolyn A BrownDivision of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA.
Vani VannappagariDivision of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA.
Annemiek de RuiterDuke Global Health Institute, Durham, NC.
Leigh RagoneDivision of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA.
Andrea L WirtzDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Savita Pahwa · 2007 to 2026
$33.8M
SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
LITE CONNECT: Addressing testing gaps and epidemiologic disparities of COVID-19 amongtransgender people in the United StatesUH3AI133669 · NIAID · JOHNS HOPKINS UNIVERSITY · PI REISNER, SARI, WIRTZ, ANDREA L · 2019 to 2022
$6.9M
American Cohort to Study HIV Acquisition among Transgender Women in High Risk AreasUG3AI133669 · NIAID · JOHNS HOPKINS UNIVERSITY · PI REISNER, SARI, WIRTZ, ANDREA L · 2017 to 2018
$3.5M
PrEP Engagement Trajectories Among Transgender Women in the United StatesF31MH124582 · NIMH · JOHNS HOPKINS UNIVERSITY · PI COONEY, ERIN EILEEN · 2020 to 2022
$138k
National Institute of Allergy and Infectious Diseases UG3/UH3AI133669NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI060354NIAID NIH HHS P30 AI073961NIAID NIH HHS P30 AI094189NIAID NIH HHS P30 AI117970NIAID NIH HHS UG3 AI133669NIAID NIH HHS UH3 AI133669NIMH NIH HHS F31 MH124582NIMH NIH HHS F31MH124582
6 · The paper itself

Abstract

backgroundAmong communities with elevated HIV burden, increased uptake of PrEP, including long-acting injectable (LAI) PrEP, could lower HIV incidence. Lack of data on LAI PrEP interest among transgender women in the United States has limited scientific understanding of the potential impact of LAI PrEP on new infections within transgender communities. Our objective was to determine the percent of transgender women interested in LAI PrEP and identify correlates of interest.

methodsTransgender women enrolled in the LITE Cohort who completed 12-month surveys between March 2019 and September 2021 were asked about interest in using LAI PrEP. Prevalence ratios (PR) estimated with modified Poisson regression models were assessed for predictors of interest in LAI PrEP.

resultsAmong 867 participants, 15% were current users of oral PrEP and 11% were former oral PrEP users. In total, 47% reported interest in LAI PrEP. Interest in LAI PrEP was more common among participants who were Black (PR: 1.28; 95% CI: 1.05 to 1.55), college-educated (PR: 1.28; 95% CI: 1.04 to 1.57), food insecure (PR: 1.19; 95% CI: 1.00 to 1.41), and had PrEP indications (PR: 1.44; 95% CI: 1.21 to 1.71). LAI PrEP interest was also more common among adherent users of oral PrEP and those who had discontinued oral PrEP, compared with PrEP-naïve participants.

conclusionsInterest in LAI PrEP among transgender women varied by demographic and clinical characteristics. Increased interest in LAI PrEP among Black transgender women, those with PrEP indications, and those who had previously discontinued oral PrEP underscores the need to increase LAI PrEP access for transgender women who are interested.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisTransgender PersonsAdolescentAdultDelayed-Action PreparationsFemaleHumansInjectionsMaleMiddle AgedUnited StatesYoung AdultAnti-HIV AgentsDelayed-Action PreparationsHIVinjectable PrEPLITE cohortlong-acting PrEPpre-exposure prophylaxistransgender womenUnited States

Identifiers

PMID40788229
PMCPMC11315400

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.