Evidence map›Paper›PMID 40788195›Full record

SynthesisVeterinary medicine and science2025

Zoonotic Tuberculosis and Dairy Products: Comprehensive Meta-Analysis of Prevalence and Public Health Implications.

Sabbir Hossen Sabuz, Israt Jahan, Bristi Kona Debnath, Md Mominul Islam, Md Sadequl Islam

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Epidemiological investigation ofOpen veterinary journal · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sabbir Hossen SabuzDeprtment of Animal Science and Nutrition, Faculty of Veterinary and Animal science, Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh.
Israt JahanDepartment of Dairy and Poultry Science, Faculty of Veterinary and Animal Science, Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh.
Bristi Kona DebnathDepartment of Anatomy and Histology, Faculty of Veterinary and Animal Science, Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh.
Md Mominul IslamDepartment of Pathology, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh.
Md Sadequl IslamDepartment of Anatomy and Histology, Faculty of Veterinary and Animal Science, Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh.ORCID 0000-0003-4198-9452

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis (TB) remains a global health concern, with unpasteurized milk serving as a major source of zoonotic Mycobacterium bovis transmission in endemic, low-resource regions.

objectiveThis meta-analysis investigates the prevalence of human TB cases linked to contaminated dairy products, assesses factors influencing transmission dynamics and identifies actionable strategies to reduce risks.

methodsA systematic meta-analysis of TB cases from contaminated dairy consumption was conducted using PubMed, Web of Science and Scopus (2000-2024). Eligible studies reported human TB prevalence. Data were extracted systematically, and statistical analyses (MedCalc) assessed heterogeneity (Cochran's Q, I

resultsThis meta-analysis reviewed 25 studies from 2000 to 2024, encompassing 10,508 samples, to assess zoonotic TB linked to dairy consumption. Detection rates ranged widely from 0.77% to 49%, with molecular methods like polymerase chain reaction (PCR) showing higher sensitivity (up to 49%) than culture techniques (21%-35%). Prevalence was greater in TB-endemic areas such as Ethiopia, Mexico and Tanzania, where raw dairy samples outperformed blood diagnostics in positivity. Notably, the highest detection rates were observed in confirmed M. bovis cases with a history of raw milk consumption, underscoring the zoonotic risk in unregulated dairy contexts. Significant heterogeneity (I

conclusionZoonotic TB from dairy products is a major concern in endemic areas due to unpasteurized milk and poor veterinary infrastructure. Enhanced pasteurization, standardized diagnostics and better surveillance are key to reducing risks, alongside global food safety standards and public health campaigns to protect vulnerable groups.

Indexed as

Dairy ProductsPublic HealthTuberculosisZoonosesAnimalsHumansMycobacterium bovisPrevalencedairy productsprevalencepublic healthzoonotic tuberculosis

Identifiers

PMID40788195
PMCPMC12337750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.