Evidence map›Paper›PMID 40788103›Full record

ReviewInfection and immunity2025

Exploring the vaginal ecosystem: insights into host-microbe interactions and microbial community dynamics.

Emily F Landolt, Jéssica da Conceição Mendonça, Abbey E Behler, Stephen W Lumsdaine, Tamanna Jafar, Lindsey R Burcham

Abstract readReview
In one paragraph

Review in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Chemotaxis and selective interactions ofbioRxiv : the preprint server for biology · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Orally ingestedFrontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily F Landolt *Department of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
Jéssica da Conceição Mendonça *Department of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
Abbey E Behler *Department of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
Stephen W LumsdaineDepartment of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
Tamanna JafarDepartment of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
Lindsey R BurchamDepartment of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.ORCID 0000-0002-5182-796X

Funding

Nutritional landscape and community interactions in the vaginal microbiomeR35GM150785 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI Lindsey Renae Burcham · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM150785NIH HHS 5R35GM150785
6 · The paper itself

Abstract

The vaginal tract is a complex environment that changes throughout various life stages. Recent advances have improved our understanding of the vaginal microbiota and the influence of host factors on microbial colonization. The vaginal niche is characterized by unique qualities such as high abundances of glycogen and mucin, low pH, active cellular immunity, and fluctuations in hormone signaling that support a complex microbiota. While traditionally thought to be dominated by

Indexed as

EcosystemHost Microbial InteractionsHost-Pathogen InteractionsMicrobiotaVaginaDysbiosisFemaleHumansMucous Membranevaginal microbiome

Identifiers

PMID40788103
PMCPMC12418763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.