ArticleJournal of agricultural and food chemistry2025
Peptide Profiling of Young Gouda Holland Cheese and Its Digests Obtained by In-Vitro-Simulated Gastrointestinal Digestion.
Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Ripened cheeses contain bioactive peptides that are released from caseins by enzymatic hydrolysis during fermentation and ripening. However, the physiological relevance of these peptides depends on their stability during gastrointestinal digestion and their bioavailability. This study aimed to assess the impact of digestion on the peptide profile of the young Gouda Holland cheese. Using liquid chromatography coupled to electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS), we monitored the peptide profile changes during in vitro simulated gastrointestinal digestion. In total, 54 peptide sequences were identified in cheese (20), gastric (20), and intestinal digests (24). Ten peptides were derived from α
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