ArticleAdvanced healthcare materials2025
Miniaturized Wireless tDCS With Concentric Electrodes for Targeted Cortical Stimulation in Freely Moving Mice.
Article in Advanced healthcare materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Battery-free, fully wireless neurostimulation via radiative RF power transfer in freely behaving mice.Microsystems & nanoengineering · 2026Article
- Ultralight infrared-controlled wireless neuromodulation systems for freely behaving mice.Microsystems & nanoengineering · 2026Article
- Miniaturized Wireless tDCS With Concentric Electrodes for Targeted Cortical Stimulation in Freely Moving Mice.Advanced healthcare materials · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Transcranial direct-current stimulation (tDCS) emerges as a promising non-invasive technique for modulating brain activity. However, conventional systems remain limited in behavioral neuroscience due to low spatial resolution and reliance on tethered setups. Here, a miniaturized, fully wireless tDCS system is presented that employs concentric electrodes (CEs) to enable focal cortical stimulation in freely moving mice. Electric field simulations confirm that the CE design more effectively restricts current spread compared to conventional electrode configurations. The CEs, fabricated using a flexible printed circuit board process, conform to the curvature of the mouse skull, ensuring stable contact and precise stimulation. The wireless system weighs 2.64 g and integrates a boost converter capable of delivering an 11 V stimulation output, along with a Bluetooth-controlled switching circuit. This compact design supports chronic implantation without restricting movement. Behavioral validation demonstrates that targeted stimulation of the left or right secondary motor cortex (M2) selectively induces direction-specific circling behavior in mice. These findings underscore the system's ability to deliver spatially confined and behaviorally effective neuromodulation. Overall, the CE-tDCS system offers a robust and high-resolution platform for investigating the causal relationships between localized brain stimulation and behavior in untethered animal models.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.