ArticleAnnals of medicine and surgery (2012)2025
Demographic and racial disparities in small-cell lung carcinoma: trends in diagnosis to treatment time, chemoradiotherapy seeking, and incidence rates-A SEER database analysis (2000-2021) with Bayesian multilevel regression modeling.
Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Small cell-lung carcinoma (SCLC) is an aggressive cancer with poor prognosis, influenced by demographic factors such as race, sex, and age. Racial and demographic disparities in SCLC incidence and treatment outcomes are evident, with minorities experiencing higher incidence rates. Understanding these disparities is essential for addressing healthcare inequities. Methods: This study analyzed 243 825 SCLC cases from the Surveillance, Epidemiology, and End Results database (2000-2021), examining demographic variables (age, sex, race) and their effects on treatment-seeking behavior and treatment delays using Bayesian multilevel regression modeling. Results: The cohort consisted of 48.2% males and 51.8% females, with a racial composition of 35.1% White, 25.5% Black, 22.5% Asian/Pacific Islander, and 16.9% American Indian/Alaska Native. American Indian/Alaska Native individuals had a higher incidence of SCLC (β = 6.47, 95% CI: 5.26-7.69, Conclusion: This study highlights significant racial and demographic disparities in SCLC incidence, particularly among minority populations. While treatment-seeking behaviors and delays did not exhibit significant racial differences, age and sex were critical factors influencing SCLC incidence.
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