Evidence map›Paper›PMID 40787529›Full record

ArticleAnnals of medicine and surgery (2012)2025

Spinal teratoma in an adolescent: a rare case report with intradural presentation and review of management strategies.

Sudarsan Agarwal, Reshma Agarwal, Sameer Kumar Majety, Ananta Kiran Kumar Veldurthi, Santhoshi Devi Koppala, Gopichand Muppana

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Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Sudarsan AgarwalDepartment of Neurosurgery, Sri Venkateswara Medical College, Tirupati, India.
Reshma AgarwalSchool of Medicine, China Medical University, Shenyang, P.R. China.
Sameer Kumar MajetySchool of Medicine, Xiamen University, Xiamen, P.R. China.
Ananta Kiran Kumar VeldurthiDepartment of Neurosurgery, Sri Venkateswara Medical College, Tirupati, India.
Santhoshi Devi KoppalaDepartment of Radiology, Sri Venkateswara Medical College, Tirupati, India.
Gopichand MuppanaNational Pirigov Memorial Medical University, Vinnytsia, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Spinal teratomas are rare tumors of pluripotent germ cells, accounting for <0.5% of all spinal cord tumors and 2% of all teratomas. While they commonly occur in gonads, extragonadal spinal presentation is uncommon. They are often associated with spinal dysraphism and present variably depending on tumor location and neural compression. MRI aids in diagnosis, but histopathological examination remains the gold standard. Early detection is vital to avoid irreversible neurological damage. Case presentation: A 16-year-old Indian male presented with progressive lower back pain for one year, followed by involuntary micturition and bilateral temporal headaches for six months. Neurological examination was normal, but persistent urinary symptoms warranted imaging. MRI revealed an intradural lesion at D11-L1, consistent with a spinal teratoma. The patient underwent surgical excision, and histopathology confirmed a monodermal teratoma. At three-month follow-up, the patient's symptoms had completely resolved. Discussion: Spinal teratomas may be classified as mature, immature, or malignant. Mature teratomas are most common in adults. Theories regarding their origin include misplaced primordial germ cells and dysembryogenic malformations. Clinical presentation varies from pain to autonomic dysfunction, demanding high clinical suspicion and prompt imaging. Surgical excision remains the mainstay of treatment. Subtotal resection is considered when tumors adhere to critical neural structures. Although rare, recurrence, malignant transformation, and aseptic meningitis have been reported, emphasizing the need for long-term follow-up. Conclusion: This case underscores the importance of early neuroimaging in patients with atypical spinal symptoms. Surgical resection is definitive, while histopathology confirms the diagnosis. Regular follow-up remains essential.

Indexed as

aseptic meningitisintradural tumormonodermal teratomaspinal teratomasurgical excision

Identifiers

PMID40787529
PMCPMC12333716

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