SynthesisFrontiers in immunology2025
Effect of acupuncture and moxibustion on the immune function of patients with malignant tumors: a systematic review and meta-analysis.
Synthesis in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of Acupuncture and Moxibustion for Non-Small Cell Lung Cancer (NSCLC) Patients Undergoing Standard Treatment: A Systematic Review and Meta-Analysis.Integrative cancer therapiesPooled it
- Acupuncture combined with immunotherapy for recurrent and metastatic cervical cancer: a pilot RCT protocol.Frontiers in oncology · 2026Trial
- Moxibustion combined with anti-PD-1 antibodies improves immunosuppression in septic mice potentially through the PD-1/PD-L1 pathway.Immunologic research · 2026Article
- Moxibustion for gastrointestinal cancer-related fatigue: study protocol for a randomized clinical trial.Frontiers in psychiatry · 2026Article
- Moxibustion combined with chemotherapy inhibits gastric cancer growth by modulating the immunosuppressive microenvironment involving the Treg/IL-10/TGF-β1 axis.Frontiers in pharmacology · 2025Article
- Moxibustion Promotes Tumor Immune Responses and Vascular Normalization to Enhance Antitumor Effect of Cisplatin in Lewis Lung Carcinoma Mice.Integrative cancer therapiesArticle
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acupuncture and moxibustion have been shown to be safe and effective methods for bidirectional immunomodulatory function. Clinical practice and many studies have shown that acupuncture and moxibustion have a certain clinical effect on immune promotion in patients with malignant tumors. Methods: Eight electronic databases were searched systematically for articles published through December 31, 2024. Study Selection Randomized controlled trial studies (RCTs) that reported The number of T lymphocytes cells in patients with malignant tumors who received acupuncture and/or moxibustionon treatment were included. For continuous variables, effect estimates were calculated as mean difference (MD); and for dichotomous variables, the risk ratio (RR) was calculated. A funnel plot was used to analyze potential publication bias. Results: 33 studies involving 2610 participants were included. Patients who received acupuncture and/or moxibustion treatment had higher CD3 Conclusions: Evidence from this meta-analysis, acupuncture and moxibustion can enhance the immune function and improve the prognosis of malignant tumor patients. Further studies are recommended to support and confirm these findings. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42023465759.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.