Evidence map›Paper›PMID 40787272›Full record

ArticleIranian journal of child neurology2025

Hypoglycemic Seizure: Etiologies and Neurological Outcome in Two Differential Age of Children (Five Year Descriptive Study).

Nahideh Khosroshahi, Masoumeh Hassani, Kamyar Kamrani, Zahra Haghshenas, Nika Keshtkaran, Simin Khayatzadeh Kakhki

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Article in Iranian journal of child neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nahideh KhosroshahiDivision of Pediatric neurology, Tehran University of Medical Sciences, School of Medicine, Bahrami Children Hospital, Tehran, Iran.
Masoumeh HassaniFaculty of Medicine, Tehran University of Medical Sciences, School of Medicine, Tehran, Iran.
Kamyar KamraniDivision of Neonatology, Tehran University of Medical Sciences, School of Medicine Bahrami Children Hospital, NICU department, Tehran, Iran.
Zahra HaghshenasDivision of Pediatric endocrinology, Tehran University of Medical Science, School of Medicine, Bahrami Children Hospital.
Nika KeshtkaranFaculty of Medicine, Tehran University of Medical Sciences, School of Medicine, Tehran, Iran.
Simin Khayatzadeh KakhkiDivision of Pediatric neurology, Tehran University of Medical Sciences, School of Medicine, Bahrami Children Hospital, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Hypoglycemia is a widespread pediatric emergency that can manifest in various ways. One of the most critical symptoms is the occurrence of seizures. Recognizing these episodes promptly is essential in managing the condition effectively. Physicians' apprehension, specifically pediatricians', can lead to early diagnosis and improve the prognosis by decreasing the neurologic aftermath. By presenting data and analysis on the prevalence of hypoglycemic seizures, triggers, and neurologic side effects, we plan to raise awareness of the issue. This study intends to demonstrate the leading causes of hypoglycemia and the major neurological sequels by assessing the prevalence of hypoglycemia in a children's hospital center to raise awareness of the condition. Materials & Methods: This cross-sectional study was conducted with two parts: demographic data (age, gender), clinical presentations, and lab data (blood sugar) on seizure onset, cause of hypoglycemia, and comorbidities before admission. The second part was based on neurologic evaluation and sequela follow-up. Results: Collectively, 79 pediatric patients were enrolled in the study, of which 51 were male (64.6%).44.3% had experienced a first episode of hypoglycemic seizures in neonacy, 24.05% in infancy, and 31.65% in childhood. In the neonatal period, poor intake, birth asphyxia, and IUGR are, respectively, the leading causes of hypoglycemic seizures. As for the infant-child group, the most common etiology was the following: diabetic patients treated with insulin, ketotic hypoglycemia, hyperinsulinism, and Glycogen Storage Disease (GSD), respectively. The most common sequelae were global psychomotor delay, isolated speech delay, and isolated motor delay, respectively. Conclusion: This study reveals that we can help prevent hypoglycemia by maternal education on breast-feeding and avoiding early patient discharge. Regarding the post-neonatal group, parental education on the proper application of insulin can prevent probable seizure and other consequences.

Indexed as

Developmental delayEpilepsyHypoglycemic seizureNeonatal seizure

Identifiers

PMID40787272
PMCPMC12330970

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