Evidence map›Paper›PMID 40787262›Full record

ArticleJournal of inflammation research2025

In vitro Study of Fungus-Like Organisms

Monika Sztandera-Tymoczek, Sylwia Wdowiak-Wróbel, Urszula Świderska, Marta Palusińska-Szysz, Agnieszka Szuster-Ciesielska

Abstract read
In one paragraph

Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Monika Sztandera-TymoczekDepartment of Virology and Immunology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland.ORCID 0000-0003-2963-3699
Sylwia Wdowiak-WróbelDepartment of Genetics and Microbiology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland.ORCID 0000-0002-5251-5335
Urszula ŚwiderskaDepartment of Botany, Mycology and Ecology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland.ORCID 0000-0002-3120-276X
Marta Palusińska-SzyszDepartment of Genetics and Microbiology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland.ORCID 0000-0001-8540-3084
Agnieszka Szuster-CiesielskaDepartment of Virology and Immunology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland.ORCID 0000-0003-4046-1920

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Allergic conditions have surged to epidemic proportions globally, affecting almost 30% of people worldwide. Fungi are a significant source of allergens, contributing to up to 6% of respiratory illnesses in the general population. Nonetheless, the exact cause of respiratory allergies often remains elusive. This research sought to explore the potential of two fungus-like species from the Peronosporales ( Materials and Methods: BEAS-2B and A549 cell lines were used to mimic upper and lower respiratory epithelial cells. The cytotoxicity of fungal extracts was assessed using MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) and flow cytometry assays. Reactive oxygen species (ROS) production in the cells was measured through flow cytometry, while ELISA (enzyme-linked immunosorbent assay) tests were used to quantify the production of proinflammatory cytokines and metalloproteinases. Immunofluorescence techniques were utilized to evaluate markers of cell integrity. Results: Although Conclusion: The results indicate that

Indexed as

airway epithelial cellsinflammatory responsePeronospora ficariaephytopathogenic microfungiWilsoniana bliti

Identifiers

PMID40787262
PMCPMC12333880

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.