Evidence map›Paper›PMID 40787252›Full record

ArticleClinical interventions in aging2025

The Safety of Blood Flow Restriction Combined with Stepping Aerobic Exercise in Older Adults with Sarcopenia.

Hui Zhang, Shulian Liu, Zhiyu Mao, Kewen Niu, Xinwei Li, Tongtong Yin, Fangfang Wang, Li Wang

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hui Zhang *School of Nursing, Suzhou Vocational Health College, Jiangsu, 215009, People's Republic of China.ORCID 0000-0001-7462-2687
Shulian Liu *Luoyang Polytechnic, Henan, 471000, People's Republic of China.
Zhiyu MaoSchool of Nursing, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, 215006, People's Republic of China.
Kewen NiuSchool of Nursing, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, 215006, People's Republic of China.
Xinwei LiSchool of Nursing, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, 215006, People's Republic of China.
Tongtong YinSchool of Nursing, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, 215006, People's Republic of China.
Fangfang WangSchool of Nursing, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, 215006, People's Republic of China.
Li WangSchool of Nursing, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, 215006, People's Republic of China.ORCID 0000-0003-2669-826X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to explore the safety of blood flow restriction combined stepping aerobic exercise (BFR-SAE) using elastic and non-elastic cuffs at varying pressures in older adults with sarcopenia. Methods: Older adults with sarcopenia were selected by convenience sampling method and underwent BFR-SAE using elastic and non-elastic cuffs at 20%, 40%, and 60% limb occlusion pressure (LOP). Exercise response and adverse events were recorded. Results: Thirty-one participants (84.81 ± 6.19 years old) completed the tests. During the non-elastic cuffs test, 31 participants completed at 20% LOP, and 4 (12.9%) dropped from 40% to 20% LOP. At 60% LOP, 19 (61.3%) and 3 (9.7%) dropped to 40% and 20% LOP, respectively. In the elastic cuffs tests all participants completed at 20% and 40% LOP. At 60% LOP, 9 (29.0%) dropped to the interface pressure corresponding to 40% LOP. General exercise responses were lower with elastic cuffs at 40% LOP (22.6% vs 45.2%) and 60% LOP (41.9% vs 51.6%), with higher completion rate than non-elastic cuffs (40% LOP: 100% vs 87.1%; 60% LOP: 71.0% vs 29.0%). Among the results of systolic and diastolic blood pressure (SBP and DBP), pulse rate (P) and pulse oxygen saturation (SpO Conclusion: Elastic cuffs for BFR-SAE induced milder exercise responses and higher completion rates, suggesting better safety and feasibility than non-elastic cuffs in older adults with possible sarcopenia.

Indexed as

Blood Flow Restriction TherapyExerciseExercise TherapySarcopeniaAgedAged, 80 and overFemaleHumansMaleaerobic exerciseblood flow restrictionolder adultssafetysarcopenia

Identifiers

PMID40787252
PMCPMC12335840

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.