ArticleFrontiers in pediatrics2025
Global, regional, and national burden of sudden infant death syndrome and the impact of COVID-19: a trend and health inequality analysis based on the global burden of disease study 2021.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- A Case of Sudden Unexpected Infant Death with Presumptive SARS-CoV-2 Infection.International journal of molecular sciences · 2026Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Current sudden infant death syndrome (SIDS) epidemiological patterns and COVID-19 impacts remain uncertain. We therefore conducted this global, regional, and national epidemiological study using data from the Global Burden of Disease Study (GBD) 2021. Methods: This study analyzed GBD-based population data on SIDS disability-adjusted life years (DALYs). Age-standardized DALY rates (ASDR; per 100,000 population) with 95% uncertainty intervals (UIs) were calculated for 204 countries and territories, stratified by age, location, and socio-demographic index (SDI). Results: In 2021, the ASDR of SIDS accounted for 44.16 (95% UI: 25.70-59.26) per 100,000 population globally, which was a 58.97% decrease from 1990. The low and low-middle SDI quintiles exhibited a disproportionately higher disease burden of SIDS among the five SDI quintiles in 2021. Higher sociodemographic status showed an inverse association with SIDS burden, with high-SDI countries demonstrating a greater reduction compared to low-SDI counterparts from 1990 to 2021 based on age-period-cohort analysis. Although the global burden of SIDS had maintained a sustained downward trend prior to the pandemic, COVID-19 disruptions may have attenuated mitigation progress, with trend analysis suggesting a possible plateau in SIDS burden during this period rather than continued decline. Study findings indicate that although the global incidence of SIDS has shown a steady decline, persistent regional disparities underscore long-standing public health challenges. Conclusion: The burden of SIDS-related DALYs remains substantial, and its post-pandemic evolution trends necessitate dynamic tracking through robust epidemiological surveillance systems.
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