Evidence map›Paper›PMID 40786986›Full record

ArticleAACE endocrinology and diabetes

Gestational Pituitary Apoplexy With Persistent Hypogonadotropic Hypogonadism.

Jana Makhlouf, Wassim Daoud Khatoun, Michel Boustany, Alissa Chebat, Mohamad Ghanem, Rita Nemr

Abstract readCase Reports
In one paragraph

Article in AACE endocrinology and diabetes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jana MakhloufDepartment of Internal Medicine, Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Wassim Daoud KhatounDepartment of Internal Medicine, Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Michel BoustanyDepartment of Internal Medicine, Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Alissa ChebatDepartment of Internal Medicine, Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Mohamad GhanemDepartment of Internal Medicine, Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Rita NemrDepartment of Endocrinology, Lebanese American University Medical Center-Rizk Hospital (LAUMCRH), Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Objective: Pituitary apoplexy (PA) is a rare and life-threatening emergency that remains prone to misdiagnosis, especially in pregnancy. Few cases of gestational PA have been reported in the literature. Case Report: This study reports a case of a 26-year-old woman presenting at 35 weeks of gestation with PA. Discussion: Initial presentation included severe headache, blurry vision, and dizziness, and conservative medical management was opted. This included stress-dose hydrocortisone, cabergoline, and levothyroxine, followed by cesarean delivery at 36 weeks of gestation. The patient retrieved normal pituitary function, except for persistent amenorrhea 2 years after. Conclusion: This is the first case of isolated persistent hypogonadotropic hypogonadism following PA in a pregnant patient and opens the discussion on the variety of potential complications of this condition.

Indexed as

endocrinologyobstetricspituitary apoplexypregnancy

Identifiers

PMID40786986
PMCPMC12332444

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.