Evidence map›Paper›PMID 40786979›Full record

ArticleFrontiers in veterinary science2025

Influence of the extent of cervical lymph node dissection and lymph nodes metastases on prognosis in a cohort of dogs with oral malignant melanoma treated by surgical resection and adjuvant anti-CSPG4 electrovaccination: a retrospective study on 77 cases.

Davide Giacobino, Matteo Olimpo, Erica Ilaria Ferraris, Greta Martinelli, Lorella Maniscalco, Mariateresa Camerino, Federica Riccardo, Federica Cavallo, Lidia Tarone, Marzia Cino and 7 more

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Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Davide GiacobinoDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Matteo OlimpoDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Erica Ilaria FerrarisDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Greta MartinelliDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Lorella ManiscalcoDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Mariateresa CamerinoAnimal Oncology and Imaging Center AG, Hünenberg, Switzerland.
Federica RiccardoDepartment of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.
Federica CavalloDepartment of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.
Lidia TaroneDepartment of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.
Marzia CinoDepartment of Medical Veterinary Science, University of Parma, Parma, Italy.
Alfredo DentiniClinica Veterinaria Tyrus, Terni, Italy.
Selina IussichMyLav La Vallonea, Veterinary Analysis Laboratory srl, Alessano, Italy.
Elena LardoneDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Luca ManasseroDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Raffaella De MariaDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Paolo BuraccoDepartment of Veterinary Sciences, University of Torino, Torino, Italy.
Emanuela MorelloDepartment of Veterinary Sciences, University of Torino, Torino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most appropriate approach to regional/sentinel lymph nodes (LN) for staging canine oral malignant melanoma (OMM) is still controversial. This study aims to retrospectively evaluate the prognostic impact of neck dissection modality and LN metastasis in a homogeneous cohort of dogs treated by surgery and adjuvant anti-CSPG4 electrovaccination. Seventy-seven dogs were enrolled and divided into two groups based on the presence (Group A, 24 dogs) or absence (Group B, 53 dogs) of histologically confirmed LN metastasis at the time of surgery. The overall LN metastatic rate was 31%; metastasis was found mostly in the mandibular lymph center (83%). Median survival time (MST) and disease-free interval (DFI) in Group A were 406 and 134 days, respectively. Although shorter, these values were not significantly different from MST and DFI in Group B (534 and 219 days, respectively;

Indexed as

CSPG4doglymph nodelymph node dissectionoral malignant melanoma

Identifiers

PMID40786979
PMCPMC12333538

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.