Evidence map›Paper›PMID 40786746›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2025

Identifying Eligibility for Specialist Intervention in COPD from UK Primary Care Data: A "Treatable Traits" Approach.

Thomas J C Ward, Catherine John, Alexander T Williams, Chiara Batini, Neil J Greening, Martin D Tobin, Michael C Steiner

Abstract readObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas J C WardDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.
Catherine JohnUniversity Hospitals of Leicester, Leicester, UK.
Alexander T WilliamsDepartment of Population Health Sciences, University of Leicester, Leicester, UK.ORCID 0000-0003-2134-7241
Chiara BatiniUniversity Hospitals of Leicester, Leicester, UK.
Neil J GreeningDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.
Martin D TobinUniversity Hospitals of Leicester, Leicester, UK.
Michael C SteinerDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.

Funding

Wellcome Trust 202849Wellcome Trust 225221Wellcome Trust GRANT 202849
6 · The paper itself

Abstract

Background: Specialist intervention in COPD is often reactive, resulting in inequalities in the provision of care. A proactive approach, in which individuals with modifiable disease are identified from primary care records, may help to tackle this inequality in access. Aim: To estimate the prevalence of "treatable traits" in COPD in a primary care research database and to assess health service usage. Methods: We performed a secondary analysis of individuals with either 1) a primary care diagnosis of COPD or 2) obstructive spirometry and history of ever smoking in a large observational study recruiting individuals aged 40-69 years old in Leicestershire, UK. Spirometry, height, weight and smoking history were collected prospectively and linked to individuals' primary care records. "Treatable traits" were identified from primary care records (frequent exacerbations, current smoking, low body mass index, respiratory failure, severe breathlessness, potential suitability for lung volume reduction or psychological comorbidity). Differences in demographics and health usage between those with and without "treatable traits" were assessed. Results: In total, of the 347 individuals with COPD, 186 had at least one "treatable trait". Compared to those without treatable traits, individuals with treatable traits were younger (61 vs 64 years, p<0.001), had more severe airflow obstruction (FEV Conclusion: Treatable traits are common in COPD and can be identified from routinely collected primary care data. Treatable traits are associated with younger age and greater deprivation. These individuals pose a significant burden to primary care yet are rarely referred to specialist respiratory services.

Indexed as

Eligibility DeterminationLungPatient SelectionPrimary Health CarePulmonary Disease, Chronic ObstructiveSpecializationAdultAgedDatabases, FactualEnglandFemaleForced Expiratory VolumeHealthcare DisparitiesHumansMaleMiddle Agedchronic respiratory diseaseintegrated caretreatable traits

Identifiers

PMID40786746
PMCPMC12335837

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.