Evidence map›Paper›PMID 40786744›Full record

ReviewBioscience nanotechnology2025

Nanomaterial scaffolds for enzymatic polymer degradation: a tool to advance current biodegradation assessments of polymers in liquid formulation.

Nick W Johnson, Sheng Yan Jiang, Samuel B H Patterson, Trevor Hinchcliffe, Filipe Vilela, Humphrey H P Yiu

Abstract readReview
In one paragraph

Review in Bioscience nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nick W JohnsonInstitute of Chemical Sciences, School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh, UK.
Sheng Yan JiangImpact Solutions Ltd., Impact Technology Centre, Fraser Road, Kirkton Campus, Livingston, UK.
Samuel B H PattersonImpact Solutions Ltd., Impact Technology Centre, Fraser Road, Kirkton Campus, Livingston, UK.
Trevor HinchcliffeImpact Solutions Ltd., Impact Technology Centre, Fraser Road, Kirkton Campus, Livingston, UK.
Filipe VilelaInstitute of Chemical Sciences, School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh, UK.
Humphrey H P YiuInstitute of Chemical Sciences, School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymers are used as an integral component in a wide range of liquid formulation products to improve formulation integrity and product performance. Due to environmental and regulatory pressures, it is necessary for the industry to shift away from petrochemically derived polymers to more sustainable and biodegradable products. However, current methods to analyse the biodegradation of polymers are time consuming and adapted to small molecules which is stifling innovation in this area. There is a requirement to re-envisage how the industry conducts biodegradability testing for polymers in liquid formulation (PLFs) from high-throughput screening methods at the preliminary stages of development to predictive modelling. Advancements in the use of nanomaterials as enzyme immobilisation scaffolds for polymer degradation could evolve how biodegradability testing is thought about and drive the PLF industry into a more sustainable future. This review highlights the current trends in the use of nanomaterials as enzyme immobilisation platforms and how this technology has been applied to the degradation of biodegradable PLFs.

Indexed as

BiodegradationEnzyme ImmobilisationFlow ChemistryNanomaterialsPolymer Degradation

Identifiers

PMID40786744
PMCPMC12333109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.