Evidence map›Paper›PMID 40786730›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2025

Recurrence and metastasis of cutaneous and subcutaneous tumors following excision with advanced surgical margin assessment.

Carley P Johnson, Gabrielle S Fontes, Edward Cheng, Ryan N Jennings, Janis M Lapsley, Hunter J Piegols, Laura E Selmic

Abstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carley P JohnsonDepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L. Tharp Street, Columbus, Ohio 43210 (Johnson, Fontes, Lapsley, Piegols, Selmic); Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, 10435 Sorrento Valley Road, Sorrento Valley, California 92121 (Cheng); Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, Columbus, Ohio 43210 (Jennings).
Gabrielle S FontesDepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L. Tharp Street, Columbus, Ohio 43210 (Johnson, Fontes, Lapsley, Piegols, Selmic); Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, 10435 Sorrento Valley Road, Sorrento Valley, California 92121 (Cheng); Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, Columbus, Ohio 43210 (Jennings).
Edward ChengDepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L. Tharp Street, Columbus, Ohio 43210 (Johnson, Fontes, Lapsley, Piegols, Selmic); Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, 10435 Sorrento Valley Road, Sorrento Valley, California 92121 (Cheng); Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, Columbus, Ohio 43210 (Jennings).
Ryan N JenningsDepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L. Tharp Street, Columbus, Ohio 43210 (Johnson, Fontes, Lapsley, Piegols, Selmic); Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, 10435 Sorrento Valley Road, Sorrento Valley, California 92121 (Cheng); Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, Columbus, Ohio 43210 (Jennings).
Janis M LapsleyDepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L. Tharp Street, Columbus, Ohio 43210 (Johnson, Fontes, Lapsley, Piegols, Selmic); Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, 10435 Sorrento Valley Road, Sorrento Valley, California 92121 (Cheng); Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, Columbus, Ohio 43210 (Jennings).
Hunter J PiegolsDepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L. Tharp Street, Columbus, Ohio 43210 (Johnson, Fontes, Lapsley, Piegols, Selmic); Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, 10435 Sorrento Valley Road, Sorrento Valley, California 92121 (Cheng); Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, Columbus, Ohio 43210 (Jennings).
Laura E SelmicDepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L. Tharp Street, Columbus, Ohio 43210 (Johnson, Fontes, Lapsley, Piegols, Selmic); Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, 10435 Sorrento Valley Road, Sorrento Valley, California 92121 (Cheng); Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, Columbus, Ohio 43210 (Jennings).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Surgical margin status can affect the risk for recurrence in dogs with cutaneous and subcutaneous masses. Histopathology is the current gold standard for margin assessment, despite evaluating small amounts of the surgical margin. Optical coherence tomography (OCT) has been described for surgical margin assessment following the excision of canine cutaneous and subcutaneous tumors. Objective: To assess the rates of recurrence and metastasis following excision with an incomplete margin on OCT and confirmed with histopathology. Animals and procedure: Seventy-one excised canine cutaneous and subcutaneous tumors underwent OCT imaging and histopathologic assessment. Results: Of 61 tumors, 51 were malignant, including 21 soft tissue sarcomas and 21 mast cell tumors. Ten dogs experienced local tumor recurrence, with 7/10 and 8/10 having incomplete margins on OCT and histopathology, respectively. Ten dogs experienced distant metastasis, with 6/10 and 8/10 having incomplete margins on OCT and histopathology, respectively. Conclusion and clinical relevance: Local recurrence occurred in tumors with predominately incomplete margins following advanced surgical margin assessment; however, not all tumors with incomplete margins developed local recurrence. Further prospective research is needed to assess the effect of entire surgical margin imaging on patient outcomes.

Indexed as

Dog DiseasesMargins of ExcisionNeoplasm Recurrence, LocalSarcomaSkin NeoplasmsSoft Tissue NeoplasmsAnimalsDogsFemaleMaleNeoplasm MetastasisTomography, Optical Coherence

Identifiers

PMID40786730
PMCPMC12330769

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.