Evidence map›Paper›PMID 40786656›Full record

ArticleMaterials today. Bio2025

Ginseng-derived nanoparticles accelerate diabetic wound healing by modulating macrophage polarization and restoring endothelial cell function.

Liangliang Fan, Xuxia Jia, Fusong Dong, Song Yang, Wenjing Li, Ronghua Zhao, Lijia Yin, Daqing Zhao, Jiawen Wang

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Advances in Research onInternational journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Extracellular vesicles and circulating nucleic acids · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liangliang FanJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, China.
Xuxia JiaJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, China.
Fusong DongJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, China.
Song YangNortheast Asia Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China.
Wenjing LiNortheast Asia Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China.
Ronghua ZhaoJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, China.
Lijia YinJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, China.
Daqing ZhaoNortheast Asia Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China.
Jiawen WangNortheast Asia Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular dysfunction and disruption of the balance between different subtypes of macrophages are key factors contributing to the poor healing of diabetic wounds. This study revealed that ginseng-derived nanoparticles (GDNPs) can promote angiogenesis and regulate macrophage polarization in the diabetic wound microenvironment, thereby promoting diabetic wound healing. GDNPs were found to significantly promote the cell viability of human umbilical vein endothelial cells (HUVECs) exposed to H

Indexed as

AngiogenesisDiabetic wound healingGinseng-derived nanoparticlesMacrophage polarization

Identifiers

PMID40786656
PMCPMC12332952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.