Evidence map›Paper›PMID 40786641›Full record

ArticleWellcome open research2024

Systems Policy Analysis for Antimicrobial Resistance Targeted Action (SPAARTA): A Research Protocol.

Raheelah Ahmad, Nina Zhu, Rishabh Jain, Jyoti Joshi, Mirfin Mpundu, Paola Amigo Gutierrez, Alison Holmes, Tillman Weyde, Rifat Atun

Abstract read
In one paragraph

Article in Wellcome open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Laboratory epidemiology ofOne health (Amsterdam, Netherlands) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raheelah AhmadDepartment of Infectious Diseases, Imperial College London Faculty of Medicine, London, England, W21NY, UK.ORCID https://orcid.org/0000-0002-4294-7142
Nina ZhuDepartment of Infectious Diseases, Imperial College London Faculty of Medicine, London, England, W21NY, UK.
Rishabh JainDepartment of Infectious Diseases, Imperial College London Faculty of Medicine, London, England, W21NY, UK.ORCID https://orcid.org/0000-0002-7150-8819
Jyoti JoshiInternational Centre for Antimicrobial Resistance Solutions, Copenhagen, Denmark.
Mirfin MpunduREACT Africa, Lusaka, Zambia.
Paola Amigo GutierrezSchool of Science & Technology, City University of London Department of Computer Science, London, England, EC1V0HB, UK.
Alison HolmesDepartment of Infectious Diseases, Imperial College London Faculty of Medicine, London, England, W21NY, UK.ORCID https://orcid.org/0000-0001-5554-5743
Tillman WeydeSchool of Science & Technology, City University of London Department of Computer Science, London, England, EC1V0HB, UK.
Rifat AtunDepartment of Infectious Diseases, Imperial College London Faculty of Medicine, London, England, W21NY, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The majority of countries (88%) have an Antimicrobial Resistance (AMR) National Action Plan (NAP V.1.0), but many remain unimplemented, and lack funding for interventions. Intervention selection requires a systematic approach to explain and predict progress. Looking beyond AMR is important to ensure the capture of systemic factors at the country level, which can impede or accelerate success. Aim: To provide innovative policy analysis to allow country comparison and refine targeted action, while developing and implementing NAPs (V.2.0). Methods: Mixed-method multi-country case study of policies and implementation strategies to address AMR across One Health. Starting with 17 countries, the sample includes each WHO region and emerging economies.This investigation of structures, processes, and outcomes has three components:a. Textual analysis of peer-reviewed literature, policy documents, global, national and state level progress reports, validated by global and in-country experts. An all-language article search conducted for 2000-2024, using broad search terms: 'Antimicrobial resistance policies', 'national action plan', 'surveillance', 'AMR systems' supplemented by hand searches. Deductive analysis using multi-disciplinary frameworks including the Expert Consensus for Implementation Research (ERIC). b. Longitudinal quantitative analysis assessing country contextual determinants and Antimicrobial Use (AMU) and AMR outcomes. Data from global health indicator repositories and international and national AMU and AMR surveillance networks are analysed using econometrics and machine learning approaches.c. Interactive Tableau dashboard development to display insights from a & b to allow visualisation and comparison of case-country AMR intervention context and components. Discussion: This protocol provides a systematic, transparent approach for countries to benchmark their own AMR strategies. The interactive dashboard will allow comparisons between country clusters by geography or economy, and enable rapid knowledge mobilisation among strategic and operational stakeholders including policy makers and planners. This protocol facilitates others to perform this structured assessment and nominate their country for the next wave of analysis.

Indexed as

‘Antimicrobial resistance policies’‘Health systems’‘national action plan’‘surveillance’

Identifiers

PMID40786641
PMCPMC12332476

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.