ArticleFrontiers in neurology2025
Functional near-infrared spectroscopy characteristics in children with autism spectrum disorder under animated video modeling therapy.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the impact of animated video modeling (AVM) on the brain function of children with autism spectrum disorder (ASD) using functional near-infrared spectroscopy (fNIRS). Methods: Fifteen children with ASD and 15 matched typically developing (TD) controls were enrolled. fNIRS was used to obtain 8-min data in quiet and visually stimulated states, with the dorsolateral prefrontal cortex, medial prefrontal cortex (mPFC), and bilateral occipital lobe as regions of interest (ROIs). Based on the concentration of oxygenated hemoglobin (HbO Result: The ASD group showed significantly lower functional connection strength. Comparison of the ROI-ROI functional connectivity strength revealed significant differences in connectivity patterns of the right dorsolateral prefrontal lobe (RDLPFC), left dorsolateral prefrontal lobe (LDLPFC), mPFC, right occipital lobe (ROL), and left occipital lobe (LOL) with other brain regions. Extremely significant differences were found between the RDLPFC/RPMC, ROL/RPMC, LOL/RPMC, and LOL/LIPL. The functional connectivity strength of children with ASD was significantly higher during visual stimulation than during the quiet test. Comparison between the ROI-ROI functional connectivity strengths revealed significant differences in the connectivity strength of the RDLPFC/LOL, LDLPFC/LIPL, mPFC/RPMC, mPFC/LPMC, mPFC/LIPL, ROL/RPM, ROL. RIPL, ROL/LIPL, and LOL/LIPL. Extremely significant differences were observed between the ROL/RPMC and ROL/RIPL. Conclusion: Animated video modeling can improve visual perception and information processing in children with ASD, by strengthening the functional connectivity between the occipital and inferior parietal cortices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.