Evidence map›Paper›PMID 40786577›Full record

ArticleCaspian journal of internal medicine2025

Spirulina-fortified salad dressing on body composition and anthropometric indices in hypertensive patients: A tipple-blind randomized placebo-controlled trial.

Elnaz Ghaem Far, Siavash Babajafari, Zohreh Ghaem Far, Salman Mohammadi, Mehran Nouri, Javad Kojuri, Elham Ashrafi-Dehkordi, Mohammad Hossein Rahmani, Seyed Mohammad Mazloomi

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In one paragraph

Article in Caspian journal of internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pharmacological insights intoFrontiers in pharmacology · 2025
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elnaz Ghaem FarDepartment of Food Technology, Engineering and Nutrition, Lund University, Sweden.
Siavash BabajafariNutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Zohreh Ghaem FarDepartment of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Salman MohammadiDepartment of Nutrition, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran.
Mehran NouriInfertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Javad KojuriDepartment of Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran.
Elham Ashrafi-DehkordiNutrition Research Center and Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Hossein RahmaniClinical Education Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Mohammad MazloomiNutrition Research Center and Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Numerous studies have demonstrated that improving anthropometric indices through a healthy diet and exercise can aid individuals with high blood pressure. Additionally, research suggests that consuming Spirulina, a type of microalga, could positively impact body composition and anthropometric indices. The purpose of this study was to determine the effects of spirulina-fortified salad dressing on anthropometric indices and body composition in patients with hypertension. Methods: Forty-eight (19 men and 22 women) patients with hypertension randomly received either spirulina-fortified salad dressing containing 2 gr spirulina (SSD, n = 22) or a placebo salad dressing (PSD, n = 19) daily for eight weeks. This study was registered at https://www.irct.ir/ (the Iranian registry of clinical trials identifier: IRCT20200404046940N1). Results: There was a change in body composition and anthropometric indices from baseline to 8 weeks. We observed that the mean change±SD of waist circumference after the SSD intervention (-2.86±4.02 cm) was significantly different from that of the PSD intervention (0.38±9.47 cm). Although no between-group difference was observed, a statistically significant reduction in body fat-free mass (FFM) occurred in the PSD group after the intervention. Meanwhile, within-group mean change±SD of body fat-free mass (FFM, 1.04±5.39 kg) and body fat mass (FM, -0.73±1.83 kg) was significant only in the SSD group. However, no significance between-group difference was observed in terms of FFM and FM changes. Conclusion: The present study's findings suggest that consuming spirulina-fortified dressing can improve the status of risk factors associated with hypertension and cardiovascular diseases.

Indexed as

Anthropometric indicesBody compositionCohen’s d valueHypertensionSpirulina

Identifiers

PMID40786577
PMCPMC12329358

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.