Laparoscopic Treatment of Severe Gastroesophageal Reflux Disease (GERD) in Schaaf-Yang Syndrome: First Report of Toupet Fundoplication.

Elisavet Kanna, Eleni Batsari, Zoi Lamprinou, Ioanna Argyri, Ioannis Skondras

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Elisavet Kanna2nd Pediatric Surgery Department, Panagiotis & Aglaia Kyriakou Childrens' Hospital, Athens, GRC.

Eleni BatsariUndergraduate student of Nursing Department, National and Kapodistrian University of Athens, Athens, GRC.

Zoi Lamprinou2nd Pediatric Surgery Department, Panagiotis & Aglaia Kyriakou Childrens' Hospital, Athens, GRC.

Ioanna ArgyriPediatric Gastroenterology, Panagiotis & Aglaia Kyriakou Childrens' Hospital, Athens, GRC.

Ioannis Skondras2nd Pediatric Surgery Department, Panagiotis & Aglaia Kyriakou Childrens' Hospital, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schaaf-Yang syndrome (SYS) is a rare genetic disorder marked by hypotonia, developmental delay, and feeding difficulties, including gastroesophageal reflux disease (GERD). We report the case of a 3-year-old boy with SYS who developed severe GERD and weight loss unresponsive to medical therapy. He underwent laparoscopic Toupet fundoplication with gastrostomy placement, resulting in complete symptom resolution and significant weight gain at one-year follow-up. To our knowledge, this is the first published report of Toupet fundoplication in a patient with SYS, highlighting its potential as a safe and effective surgical option for GERD management in this rare population.

Indexed as

laparoscopic fundoplicationlaparoscopic toupet fundoplicationminimal invasive surgerypediatric gastroesophageal reflux diseaseschaaf-yang syndrome

Identifiers

PMID40786426

DOI10.7759/cureus.87726

PMCPMC12335827

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