Evidence map›Paper›PMID 40786401›Full record

ArticleCureus2025

Vertebral Artery Dissection Following High Velocity Low Amplitude Cervical Manipulation: A Case Report.

Kevin Szafran, YuanDian Zheng, Forrest Butensky

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kevin SzafranPhysical Medicine and Rehabilitation, American University of the Caribbean School of Medicine, Florida, USA.
YuanDian ZhengFamily Medicine, Nassau University Medical Center, New York, USA.
Forrest ButenskyPhysical Medicine and Rehabilitation, Nassau University Medical Center, East Meadow, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vertebral artery dissection (VAD) is a rare but potentially serious cause of posterior circulation stroke, occasionally associated with high-velocity, low-amplitude cervical spinal manipulation therapy (CSMT). We present the case of a 70-year-old female who developed acute expressive aphasia following chiropractic neck manipulation. Imaging revealed a proximal right vertebral artery occlusion with findings suggestive of dissection in the setting of vascular hypoplasia. The patient was managed conservatively with blood pressure control, antithrombotic therapy, and rehabilitation, ultimately returning to near-baseline function. This case highlights the importance of recognizing VAD as a potential complication of cervical manipulation and underscores the value of early diagnosis, thorough vascular imaging, and multidisciplinary management.

Indexed as

cervical spine manipulationexpressive aphasiamiddle cerebral artery aneurysmtraumatic vertebral artery dissectionvertebrobasilar ischemia

Identifiers

PMID40786401
PMCPMC12335355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.