Evidence map›Paper›PMID 40786378›Full record

ArticleCureus2025

Undiagnosed Subacute Bioprosthetic Aortic Valve Abscess Leading to Complete Heart Block Requiring Permanent Pacemaker Insertion: A Case Report.

Kamran Dawood, Faraz S Rana, Zahid Khan, Arun Ranjit

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kamran DawoodCardiology, Mid and South Essex National Health Service (NHS) Foundation Trust, Southend-on-Sea, GBR.
Faraz S RanaCardiology, Aintree University Hospital, Liverpool University Hospitals National Health Service (NHS) Foundation Trust, Liverpool, GBR.
Zahid KhanCardiology, University of South Wales, Pontypridd, GBR.
Arun RanjitCardiology, Aintree University Hospital, Liverpool University Hospitals National Health Service (NHS) Foundation Trust, Liverpool, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic root abscess is a rare and serious complication of infective endocarditis (IE). The presentation can be vague, and a high degree of suspicion is usually required. We present the case of a 78-year-old woman with a previous history of aortic valve replacement (AVR) surgery eight months ago who presented to the Accident and Emergency (A&E) department after falling at home. After initial scrutiny, her electrocardiogram (ECG) showed complete heart block, for which she received a dual-chamber permanent pacemaker. At that time, due to suspected chest infection, her laboratory tests showed slightly elevated C-reactive protein levels, but blood cultures and chest radiography did not show any evidence of infection. She was administered oral antibiotics for a chest infection and underwent successful pacemaker implantation. After approximately a week, she presented again with generalized weakness and collapse without loss of consciousness. Repeated blood tests showed elevated inflammatory markers, and blood cultures were positive for

Indexed as

antibiotic administration in the management of severe sepsisdevice-associated endocarditisminimally invasive aortic valve replacementorgan failure from sepsispermanent pacemaker implantation (ppm)s. anginosus endocarditissurgical aortic valve replacement (savr)trans aortic valve replacementtranscutaneous aortic valve replacementtransthoracic echocardiogram

Identifiers

PMID40786378
PMCPMC12335734

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.