Evidence map›Paper›PMID 40786356›Full record

ArticleCureus2025

Inadequate Reporting in Randomized Trials: A Silent Threat to Evidence Synthesis.

Himel Mondal, Seshadri Reddy Varikasuvu, Pradosh Kumar Sarangi

Abstract readEditorial
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Himel MondalPhysiology, All India Institute of Medical Sciences, Deoghar, Jharkhand, IND.
Seshadri Reddy VarikasuvuBiochemistry, All India Institute of Medical Sciences, Deoghar, Jharkhand, IND.
Pradosh Kumar SarangiRadiodiagnosis, All India Institute of Medical Sciences, Deoghar, Jharkhand, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systematic reviews and meta-analyses are central to evidence-based medicine, but their validity depends on the quality and completeness of the included randomized controlled trials (RCTs). Despite the existence of guidelines such as the Consolidated Standards of Reporting Trials (CONSORT), inadequate reporting remains a widespread issue, often impeding data extraction and synthesis. Common gaps include the type of RCT, randomization methods, group-wise sample sizes, dropout details, and primary outcome data. Poor reporting threatens the transparency, reproducibility, and utility of clinical research, ultimately compromising the reliability of systematic reviews and the clinical guidelines based on them. To address this, strict adherence to reporting standards must be enforced by journals, reviewers, and funding bodies. Researchers should be encouraged to share tabulated core trial information in public repositories. Educational efforts targeting early-career researchers and stricter accountability mechanisms are crucial. Incomplete reporting must be recognized as a serious obstacle to evidence synthesis and treated as a significant threat to the scientific enterprise.

Indexed as

clinical trialconsortgraderandomized clinical trialrandomized controlled trialreporting guidelinesystematic reviewsystematic review and meta-analysis

Identifiers

PMID40786356
PMCPMC12335382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.