ArticleCureus2025
Acute Gamma-Hydroxybutyrate (GHB) Intoxication Requiring Hemodialysis in Southern Brazil: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gamma-hydroxybutyrate (GHB) is a central nervous system (CNS) depressant with psychoactive and anesthetic properties, increasingly implicated in recreational use and drug-facilitated crimes. Its effects are amplified when combined with alcohol, posing diagnostic and therapeutic challenges in emergency settings due to its rapid metabolism and frequent co-ingestion with other substances. We describe two cases of severe GHB intoxication in adult male patients resulting in bradycardia, respiratory depression, and decreased level of consciousness requiring orotracheal intubation and intensive care unit (ICU) stabilization. Awareness of GHB's clinical profile is essential for timely diagnosis and treatment. Given its association with drug-facilitated sexual assault and the potential for life-threatening outcomes, healthcare professionals must maintain a high index of suspicion and initiate appropriate supportive measures promptly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.