Evidence map›Paper›PMID 40786316›Full record

ArticleCureus2025

Squamous Papilloma of the Esophagus in a Patient With Refractory Gastroesophageal Reflux Disease.

Shivam Gandhi, Wesam Frandah, John Diks

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Managing reflux after tubular gastric esophageal substitution.World journal of gastrointestinal surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shivam GandhiGastroenterology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Wesam FrandahInternal Medicine/Gastroenterology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
John DiksPathology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a 35-year-old woman with persistent gastroesophageal reflux disease (GERD) despite lifestyle modification and medical therapy. Endoscopy revealed a squamous papilloma in the distal esophagus, a rare benign lesion linked to chronic mucosal irritation. The lesion was excised, and histopathology confirmed squamous papilloma without dysplasia. This case underscores the importance of endoscopic evaluation in patients with uncontrolled reflux and highlights the potential link between GERD and benign esophageal neoplasms.

Indexed as

endoscopyesophagusgastroesophageal reflux diseaserefractory gerdsquamous papilloma

Identifiers

PMID40786316
PMCPMC12335381

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.