Behind the Headache: A Case of Cerebral Venous Thrombosis Associated With Hormonal Contraceptive Use.

Adélia F Sá, Bárbara G Moreira, Mariana S Alves, Rute C Gonçalves, Sandra Ferreira

Abstract readCase Reports

In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Isolated Cortical Vein Thrombosis in a Young Woman on Transdermal Ethinyl Estradiol: Case Report and Literature Review.AACE endocrinology and diabetes
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adélia F SáFamily Medicine, Unidade de Saúde Familiar (USF) Gil Eanes, Unidade Local de Saúde (ULS) do Alto Minho, Viana do Castelo, PRT.

Bárbara G MoreiraFamily Medicine, Unidade de Saúde Familiar (USF) Gil Eanes, Unidade Local de Saúde (ULS) do Alto Minho, Viana do Castelo, PRT.

Mariana S AlvesFamily Medicine, Unidade de Saúde Familiar (USF) Gil Eanes, Unidade Local de Saúde (ULS) do Alto Minho, Viana do Castelo, PRT.

Rute C GonçalvesFamily Medicine, Unidade de Saúde Familiar (USF) Gil Eanes, Unidade Local de Saúde (ULS) do Alto Minho, Viana do Castelo, PRT.

Sandra FerreiraObstetrics and Gynecology, Hospital de Santa Luzia, Unidade Local de Saúde (ULS) do Alto Minho, Viana do Castelo, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral venous thrombosis is an uncommon but potentially life-threatening condition. We present the case of a previously healthy 26-year-old woman who developed cerebral venous thrombosis while using a combined hormonal contraceptive. She presented with progressive headaches unresponsive to analgesics. Imaging confirmed thrombosis in the left transverse and sigmoid sinuses and the left internal jugular vein. Anticoagulation was initiated with full resolution of symptoms and thrombus. Extensive thrombophilia screening was negative, and combined hormonal contraceptive use was identified as the main risk factor. The patient transitioned to a progestogen-only method. This case highlights the need to consider cerebral venous thrombosis in women with atypical headaches using combined hormonal contraceptives. It also emphasizes the importance of personalized contraceptive counseling based on thrombotic risk factors.

Indexed as

adverse effectscase reportcerebral venous thrombosiscombined hormonal contraceptivescontraceptive counselingsecondary headachevenous thromboembolism

Identifiers

PMID40786304

DOI10.7759/cureus.87580

PMCPMC12334955

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.