Evidence map›Paper›PMID 40786284›Full record

ReviewCureus2025

Erector Spinae Plane Block Versus Caudal Block in Children: A Systematic Review and Meta-Analysis.

Alexa Chedid, Rawan Masarwa, Rodrigo Muscogliati, Khaled Younes, Aya Hassanieh, Dima Ezzedine, Leen Najem, Caren Safi, Zeina Najem, Neel Badhe and 2 more

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexa ChedidMedical School, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, LBN.
Rawan MasarwaCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals National Health Service (NHS) Trust, Nottingham, GBR.
Rodrigo MuscogliatiMedical School, Hull York Medical School, University of York, York, GBR.
Khaled YounesMedical School, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, LBN.
Aya HassaniehMedical School, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, LBN.
Dima EzzedineMedical School, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, LBN.
Leen NajemMedical School, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, LBN.
Caren SafiMedical School, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, LBN.
Zeina NajemMedical School, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, LBN.
Neel BadheMedical School, University of Cambridge, Cambridge, GBR.
Krystel MalekMedical School, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, LBN.
Elie NajjarCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals National Health Service (NHS) Trust, Nottingham, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erector spinae plane block (ESPB) and caudal epidural block (CEB) are two regional anaesthetic techniques used in paediatric surgical analgesia. While CEB is a well-established method, ESPB has gained increasing interest due to its potential for prolonged analgesia. This systematic review and meta-analysis compared the efficacy and safety of ESPB and CEB in paediatric patients undergoing surgery. Nine randomised controlled trials (n = 612) were included. The primary outcome was time to first rescue analgesia, with secondary outcomes including the Face, Legs, Activity, Cry, and Consolability (FLACC) pain scores and adverse events. A random-effects model was applied due to high heterogeneity (I² > 90%). ESPB significantly prolonged the time to first rescue analgesia compared to CB (standard mean difference (SMD) = 2.75, p < 0.0001). At 24 hours postoperatively, ESPB showed improved FLACC scores (SMD = 0.25, p = 0.03), while CEB provided better analgesia at one hour (SMD = 0.51, p = 0.04). However, a similar proportion of patients in the ESPB group required rescue analgesia when compared to the CEB group (70% vs. 60%, p = 0.62), raising questions about its clinical benefit despite the longer duration of effect. Both techniques demonstrated low and comparable complication rates. ESPB appears to be a safe and effective alternative to CEB, offering prolonged analgesia with similar safety outcomes. However, the clinical relevance of its extended duration is limited by the comparable need for rescue analgesia. Future large-scale, standardised studies are needed to clarify its role in paediatric anaesthesia.

Indexed as

caudal blockerector spinae plane blockpain managementpediatricrescue analgesia

Identifiers

PMID40786284
PMCPMC12332799

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.